CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027834
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Slc25a27 
Protein Synonyms/Alias
 Solute carrier family 25, member 27, isoform CRA_b; Uncoupling protein UCP-4, isoform a 
Gene Name
 Slc25a27 
Gene Synonyms/Alias
 Ucp-4; Ucp4; rCG_43627 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
165GKRRLEGKPLRFRGVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 322 AA 
Protein Sequence
MPFPEEESLQ PLTQRWPRTS KFLLSGCAAT VAELATFPLD LTKTRLQMQG EAALAKLGDG 60
AMESAPYRGM MRTALGIVQE EGFLKLWQGV TPAIYRHVVY SGGRMVTYEH LREVVFGKSE 120
DEHYPLWKSV IGGMMAGVIG QFLANPTDLV KVQMQMEGKR RLEGKPLRFR GVHHAFAKIL 180
AEGGIRGLWA GWIPNIQRAA LVNMGDLTTY DTVKHYLVLN TALEDNIATH GLSSLCSGLV 240
ASILGTPADV IKSRIMNQPR DKQGRGLLYK SSTDCVIQAV QGEGFLSLYK GFLPSWLRMT 300
PWSMVFWLTY EKIRQLSGVS PF 322 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:RGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0043025; C:neuronal cell body; IDA:RGD.
 GO:0035356; P:cellular triglyceride homeostasis; IDA:RGD.
 GO:0048839; P:inner ear development; IEP:RGD.
 GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.
 GO:0010917; P:negative regulation of mitochondrial membrane potential; IDA:RGD.
 GO:0070997; P:neuron death; IMP:RGD.
 GO:0008284; P:positive regulation of cell proliferation; IDA:RGD.
 GO:0051562; P:reduction of mitochondrial calcium ion concentration; IMP:RGD.
 GO:0046324; P:regulation of glucose import; IDA:RGD.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS