| Tag | Content |
|---|
| CPLM ID | CPLM-025581 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Histone H4 |
Protein Synonyms/Alias | |
Gene Name | Tc00.1047053507941.150, Tc00.1047053507941.160,Tc00.1047053507941.170, Tc00.1047053508203.20, Tc00.1047053508203.29,Tc00.1047053508203.38, Tc00.1047053508203.47, Tc00.1047053508203.56,Tc00.1047053510351.11, Tc00.1047053510351.20, Tc00.1047053510351.31 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Trypanosoma cruzi (strain CL Brener) |
NCBI Taxa ID | 353153 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 5 | ***MAKGKKSGEAKG | acetylation | [1] | | 11 | GKKSGEAKGTQKRQK | acetylation | [1] | | 15 | GEAKGTQKRQKKILR | acetylation | [1] | | 58 | DEVRGVIKSFVEGVV | acetylation | [1] |
|
Reference | [1] Post-translational modifications of Trypanosoma cruzi histone H4. da Cunha JP, Nakayasu ES, de Almeida IC, Schenkman S. Mol Biochem Parasitol. 2006 Dec;150(2):268-77. [ PMID: 17010453] |
Functional Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). |
Sequence Annotation | |
Keyword | Chromosome; Complete proteome; DNA-binding; Nucleosome core; Nucleus. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 100 AA |
Protein Sequence | MAKGKKSGEA KGTQKRQKKI LRENVRGITR GSIRRLARRG GVKRISGVIY DEVRGVIKSF 60
VEGVVRDATA YTEYSRKKTV TAVDVVNALR KRGKILYGYA 100 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |