| Tag | Content |
|---|
| CPLM ID | CPLM-013981 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 684 |
Protein Synonyms/Alias | |
Gene Name | ZNF684 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 96 | PGKHRESKDNFLKSV | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 8 79 KRAB.
ZN_FING 159 181 C2H2-type 1.
ZN_FING 187 209 C2H2-type 2.
ZN_FING 215 237 C2H2-type 3.
ZN_FING 243 265 C2H2-type 4.
ZN_FING 271 293 C2H2-type 5.
ZN_FING 299 321 C2H2-type 6.
ZN_FING 327 349 C2H2-type 7.
ZN_FING 355 377 C2H2-type 8. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 378 AA |
Protein Sequence | MISFQESVTF QDVAVDFTAE EWQLLDCAER TLYWDVMLEN YRNLISVGCP ITKTKVILKV 60
EQGQEPWMVE GANPHESSPE SDYPLVDEPG KHRESKDNFL KSVLLTFNKI LTMERIHHYN 120
MSTSLNPMRK KSYKSFEKCL PPNLDLLKYN RSYTVENAYE CSECGKAFKK KFHFIRHEKN 180
HTRKKPFECN DCGKAYSRKA HLATHQKIHN GERPFVCNDC GKAFMHKAQL VVHQRLHTGE 240
KPYECSQCGK TFTWNSSFNQ HVKSHTLEKS FECKECGKTF RYSSSLYKHS RFHTGEKPYQ 300
CIICGKAFGN TSVLVTHQRI HTGEKPYSCI ECGKAFIKKS HLLRHQITHT GEKPYECNRC 360
GKAFSQKSNL IVHQKIHT 378 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |