CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012654
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger and BTB domain-containing protein 6 
Protein Synonyms/Alias
 Zinc finger protein 482; Zinc finger protein with interaction domain 
Gene Name
 ZBTB6 
Gene Synonyms/Alias
 ZID; ZNF482 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68QFLLTQSKHVRITILubiquitination[1]
392HCCDMDFKHKSALKKubiquitination[1]
419KLSRPDLKRQSLL**ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 33 97 BTB.
 ZN_FING 301 323 C2H2-type 1.
 ZN_FING 326 348 C2H2-type 2.
 ZN_FING 354 376 C2H2-type 3.
 ZN_FING 382 405 C2H2-type 4.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 424 AA 
Protein Sequence
MAAESDVLHF QFEQQGDVVL QKMNLLRQQN LFCDVSIYIN DTEFQGHKVI LAACSTFMRD 60
QFLLTQSKHV RITILQSAEV GRKLLLSCYT GALEVKRKEL LKYLTAASYL QMVHIVEKCT 120
EALSKYLEID LSMKNNNQHT DLCQSSDPDV KNEDENSDKD CEIIEISEDS PVNIDFHVKE 180
EESNALQSTV ESLTSERKEM KSPELSTVDI GFKDNEICIL HVESISTAGV ENGQFSQPCT 240
SSKASMYFSE TQHSLINSTV ESRVAEVPGN QDQGLFCENT EGSYGTVSEI QNLEEGYSLR 300
HQCPRCPRGF LHVENYLRHL KMHKLFLCLQ CGKTFTQKKN LNRHIRGHMG IRPFQCTVCL 360
KTFTAKSTLQ DHLNIHSGDR PYKCHCCDMD FKHKSALKKH LTSVHGRSSG EKLSRPDLKR 420
QSLL 424 
Gene Ontology
 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0003677; F:DNA binding; TAS:ProtInc.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00651; BTB
 PF00096; zf-C2H2 
SMART
 SM00225; BTB
 SM00355; ZnF_C2H2 
PROSITE
 PS50097; BTB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS