CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008506
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Endoplasmic reticulum resident protein 29 
Protein Synonyms/Alias
 ERp29; Endoplasmic reticulum resident protein 31; ERp31 
Gene Name
 Erp29 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
54YKVIPKSKFVLVKFDacetylation[1]
69TQYPYGEKQDEFKRLacetylation[1]
204KWASQYLKIMGKILDacetylation[1]
226SELARISKLIENKMSacetylation[1]
236ENKMSEGKKEELQRSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. 
Sequence Annotation
 MOTIF 257 260 Prevents secretion from ER.  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Reference proteome; Signal; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 260 AA 
Protein Sequence
MAAAVPGAVS LSPLLSVLLG LLLLSAPHGA SGLHTKGALP LDTVTFYKVI PKSKFVLVKF 60
DTQYPYGEKQ DEFKRLAENS ASSDDLLVAE VGISDYGDKL NMELSEKYKL DKESYPVFYL 120
FRDGDFENPV PYSGAVKVGA IQRWLKGQGV YLGMPGCLPA YDALAGQFIE ASSREARQAI 180
LKQGQDGLSG VKETDKKWAS QYLKIMGKIL DQGEDFPASE LARISKLIEN KMSEGKKEEL 240
QRSLNILTAF RKKGAEKEEL 260 
Gene Ontology
 GO:0005788; C:endoplasmic reticulum lumen; TAS:RGD.
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0030133; C:transport vesicle; IDA:RGD.
 GO:0006886; P:intracellular protein transport; TAS:RGD.
 GO:0006457; P:protein folding; TAS:RGD.
 GO:0009306; P:protein secretion; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR016855; ER_p29.
 IPR011679; ER_p29_C.
 IPR012883; ERp29_N.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF07749; ERp29
 PF07912; ERp29_N 
SMART
  
PROSITE
 PS00014; ER_TARGET 
PRINTS