CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016393
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Relaxin-3 receptor 1 
Protein Synonyms/Alias
 RLN3 receptor 1; G protein-coupled receptor SALPR homolog; Relaxin family peptide receptor 3 
Gene Name
 Rxfp3 
Gene Synonyms/Alias
 Rln3r1; Salpr 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
404REFRKALKNLLWRIAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation (By similarity). 
Sequence Annotation
 CARBOHYD 36 36 N-linked (GlcNAc...) (Potential).
 CARBOHYD 40 40 N-linked (GlcNAc...) (Potential).
 DISULFID 155 247 By similarity.  
Keyword
 Cell membrane; Complete proteome; Disulfide bond; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 472 AA 
Protein Sequence
MQVASATPAA TVRKAAAGDE LSEFFALTPD LLEVANASGN ASLQLQDLWW ELGLELPDGA 60
APGHPPGGGG AESTDTEARV RILISAVYWV VCALGLAGNL LVLYLMKSKQ GWRKSSINLF 120
VTNLALTDFQ FVLTLPFWAV ENALDFKWPF GKAMCKIVSM VTSMNMYASV FFLTAMSVAR 180
YHSVASALKS HRTRGRGRGD CCGQSLRESC CFSAKVLCGL IWASAALASL PNAIFSTTIR 240
VLGEELCLMH FPDKLLGWDR QFWLGLYHLQ KVLLGFLLPL SIISLCYLLL VRFISDRRVV 300
GTTDAVGAAA APGGGLSTAS ARRRSKVTKS VTIVVLSFFL CWLPNQALTT WSILIKFNAV 360
PFSQEYFQCQ VYAFPVSVCL AHSNSCLNPI LYCLVRREFR KALKNLLWRI ASPSLTNMRP 420
FTATTKPEPE DHGLQALAPL NAAAEPDLIY YPPGVVVYSG GRYDLLPSSS AY 472 
Gene Ontology
 GO:0016021; C:integral to membrane; IC:MGI.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0008528; F:G-protein coupled peptide receptor activity; IDA:MGI.
 GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
 GO:0051482; P:elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:MGI. 
Interpro
 IPR000826; Formyl_pep_rcpt.
 IPR000276; GPCR_Rhodpsn.
 IPR017452; GPCR_Rhodpsn_7TM. 
Pfam
 PF00001; 7tm_1 
SMART
  
PROSITE
 PS00237; G_PROTEIN_RECEP_F1_1
 PS50262; G_PROTEIN_RECEP_F1_2 
PRINTS
 PR00526; FMETLEUPHER.
 PR00237; GPCRRHODOPSN.