CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032448
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MON2 protein 
Protein Synonyms/Alias
 Protein MON2 homolog 
Gene Name
 MON2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
281RVCPLVIKLFSPNIKubiquitination[1]
288KLFSPNIKFRQGSSTubiquitination[1, 2]
870LLLLNPLKEMSNINHubiquitination[2]
1218RTDSIGEKLGRYSSSubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1711 AA 
Protein Sequence
MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA ARNTEILAAL 60
KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS ETAAGNIINM LWQLMENSLE 120
ELKLLQTVLV LLTTNTVVHD EALSKAIVLC FRLHFTKDNI TNNTAAATVR QVVTVVFERM 180
VAEDERHRDI IEQPVLVQGN SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE 240
MTRTFGLELL ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA 300
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW LRAVAVESIH 360
RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL FLVPPTGNPA TSNQAGNNNL 420
GGSVSAPANS GMVGIGGGVT LLPAFEYRGT WIPILTITVQ GSAKATYLEM LDKVEPPTIP 480
EGYAMSVAFH CLLDLVRGIT SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM 540
DKEIVSRAVW EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS 600
RDAFITAICK GSLPPHYALT VLNTTTAATL SNKSYSVQGQ SVMMISPSSE SHQQVVAVGQ 660
PLAVQPQGTV MLTSKNIQCM RTLLNLAHCH GAVLGTSWQL VLATLQHLVW ILGLKPSSGG 720
ALKPGRAVEG PSTVLTTAVM TDLPVISNIL SRLFESSQYL DDVSLHHLIN ALCSLSLEAM 780
DMAYGNNKEP SLFAVAKLLE TGLVNMHRIE ILWRPLTGHL LEVCQHPNSR MREWGAEALT 840
SLIKAGLTFN HDPPLSQNQR LQLLLLNPLK EMSNINHPDI RLKQLECVLQ ILQSQGDSLG 900
PGWPLVLGVM GAIRNDQGES LIRTAFQCLQ LVVTDFLPTM PCTCLQIVVD VAGSFGLHNQ 960
ELNISLTSIG LLWNISDYFF QRGETIEKEL NKEEAAQQKQ AEEKGVVLNR PFHPAPPFDC 1020
LWLCLYAKLG ELCVDPRPAV RKSAGQTLFS TIGAHGTLLQ HSTWHTVIWK VLFHLLDRVR 1080
ESSTTADKEK IESGGGNILI HHSRDTAEKQ WAETWVLTLA GVARIFNTRR YLLQPLGDFS 1140
RAWDVLLDHI QSAALSKNNE VSLAALKSFQ EILQIVSPVR DSDKPETPPV VNVPVPVLIG 1200
PISGMSRPFV RTDSIGEKLG RYSSSEPPIV TDELEDLNLW WAAWNTWYRI GSESTKPPIT 1260
FDKLTFIPSQ PFLTALIQIF PALYQHIKTG FNMDDLQKLG VILHSAISVP ISSDASPFIL 1320
PSYTEAVLTS LQEAVLTALD VLQKAICVGP ENMQIMYPAI FDQLLAFVEF SCKPPQYGQL 1380
ETKHIANAKY NQAEWVALNY VPFAERSLEV VVDLYQKTAC HKAVVNEKVL QNIIKTLRVP 1440
LSLKYSCPSE STWKLAVSSL LRVLSIGLPV ARQHASSGKF DSMWPELANT FEDFLFTKSI 1500
PPDNLSIQEF QRNENIDVEV VQLISNEILP YANFIPKEFV GQIMTMLNKG SIHSQSSSFT 1560
EAEIDIRLRE EFSKMCFETL LQFSFSNKVT TPQEGYISRM ALSVLLKRSQ DVLHRYIEDE 1620
RLSGKCPLPR QQVTEIIFVL KAVSTLIDSL KKTQPENVDG NTWAQVIALY PTLVECITCS 1680
SSEVCSALKE ALVPFKDFMQ PPASRVQNGE S 1711 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR015403; DUF1981_SEC7_assoc.
 IPR026829; MON2. 
Pfam
 PF09324; DUF1981 
SMART
  
PROSITE
  
PRINTS