CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043066
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 POU domain, class 2, transcription factor 1 
Protein Synonyms/Alias
  
Gene Name
 POU2F1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
295PQSQSTPKRIDTPSLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 528 AA 
Protein Sequence
MADGGAASQD ESSAAAAAAA DSRMNNPSET SKPSMESGDG NTGTQTNGLD FQKQPVPVGG 60
AISTAQAQAF LGHLHQVQLA GTSLQAAAQS LNVQSKSNEE SGDSQQPSQP SQQPSVQAAI 120
PQTQLMLAGG QITGLTLTPA QQQLLLQQAQ AQAQLLAAAV QQHSASQQHS AAGATISASA 180
ATPMTQIPLS QPIQIAQDLQ QLQQLQQQNL NLQQFVLVHP TTNLQPAQFI ISQTPQGQQG 240
LLQAQNLLTQ LPQQSQANLL QSQPSITLTS QPATPTRTIA ATPIQTLPQS QSTPKRIDTP 300
SLEEPSDLEE LEQFAKTFKQ RRIKLGFTQG DVGLAMGKLY GNDFSQTTIS RFEALNLSFK 360
NMCKLKPLLE KWLNDAENLS SDSSLSSPSA LNSPGIEGLS RRRKKRTSIE TNIRVALEKS 420
FLENQKPTSE EITMIADQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS SPIKAIFPSP 480
TSLVATTPSL VTSSAATTLT VSPVLPLTSA AVTNLSALQT PPPTTQQP 528 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 
Interpro
 IPR017970; Homeobox_CS.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR010982; Lambda_DNA-bd_dom.
 IPR013847; POU.
 IPR000327; POU_specific.
 IPR000972; TF_octamer. 
Pfam
 PF00046; Homeobox
 PF00157; Pou 
SMART
 SM00389; HOX
 SM00352; POU 
PROSITE
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2
 PS00035; POU_1
 PS00465; POU_2
 PS51179; POU_3 
PRINTS
 PR00029; OCTAMER.
 PR00028; POUDOMAIN.