CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010012
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Spermidine/putrescine import ATP-binding protein PotA 
Protein Synonyms/Alias
  
Gene Name
 potA 
Gene Synonyms/Alias
 MPN_055; MP099 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
190QRLVQLTKEWESLSKacetylation[1]
261KQNEPVDKLQLKLQTacetylation[1]
265PVDKLQLKLQTLKQKacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system (By similarity). 
Sequence Annotation
 DOMAIN 7 449 ABC transporter.
 NP_BIND 40 47 ATP (Potential).
 REGION 108 318 Insert.  
Keyword
 ATP-binding; Cell membrane; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 560 AA 
Protein Sequence
MNERFLIEIE GLNKTFDDGF VSVRDINLKI KKGEFITILG PSGCGKTTTL RLLAGFEDPT 60
YGKIKVNGLD IKDLPIHKRP FATVFQDYAL FSHLTVYKNI AYGLKAMYTK LDPIDKLVEQ 120
YHQSLLDKQH RLHKRIERLE KSNANPQLLE QLKQTVVVQQ KQFKQQTETF KQKENARRDA 180
IQQRLVQLTK EWESLSKQKL QQLEAEKKLL DKKFEQTERK YQKDAWMATH SEMRLKQFKQ 240
EVLALKQLIK TKFKQNEPVD KLQLKLQTLK QKYAAKRQID KEYDKLVLAY NKKDYWTSYW 300
ETYSLQQQEA FEKRYLSRKL TKQEQHQKVC AVIELVGLKG NEDKLPEELS GGMKQRVALA 360
RSLVIEPDIL LLDEPLSALD AKVRKNLQKE LQKIHQQSGL TFILVTHDQE EALVLSNRIV 420
VMNEGNILQV GSPADIYDSP KTEWIANFIG QANIFKGTYL GDLKIKLHSG EVIKTDVDNN 480
YVVGKEYKIL IRPEDFDIVP KNKGFFNVRV IDKTYKGLLW KITTKLVDDT IVDLESVNDI 540
EVDKTFGVTF DPIDVHLMEV 560 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0015594; F:putrescine-importing ATPase activity; IEA:InterPro.
 GO:0015595; F:spermidine-importing ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR017879; ABC_Sperm/Put_ATP-bd_PotA.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR008995; Mo/tungstate-bd_C_term_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2
 PS51305; POTA 
PRINTS