CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017616
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-galactosidase-1-like protein 3 
Protein Synonyms/Alias
  
Gene Name
 GLB1L3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34SGFAPRFKQEENFMLubiquitination[1]
62HLTPLELKNRSVGLGubiquitination[1]
191LLLRTTNKSFIEAVEubiquitination[1]
233NEYGSFNKDKTYMPYubiquitination[1]
235YGSFNKDKTYMPYLHubiquitination[1]
243TYMPYLHKALLRRGIubiquitination[1]
290DTFNQLHKVQRDKPLubiquitination[1]
646MMSGSDIKSTDKPTLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 ACT_SITE 227 227 Proton donor (By similarity).
 ACT_SITE 301 301 Nucleophile (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Glycosidase; Hydrolase; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 653 AA 
Protein Sequence
MKSPPLLSPC LSWKRMAGIF FLPFISSGFA PRFKQEENFM LGRAHPSQPR FNWSHLTPLE 60
LKNRSVGLGT ESTGRGKPHF TLEGHKFLIF GGSIHYFRVP REYWRDRLLK LKACGFNTVT 120
TYVPWNLHEP ERGKFDFSGN LDLEAFVLMA AEIGLWVILR PGRYICSEMD LGGLPSWLLQ 180
DPRLLLRTTN KSFIEAVEKY FDHLIPRVIP LQYRQAGPVI AVQVENEYGS FNKDKTYMPY 240
LHKALLRRGI VELLLTSDGE KHVLSGHTKG VLAAINLQKL HQDTFNQLHK VQRDKPLLIM 300
EYWVGWFDRW GDKHHVKDAK EVEHAVSEFI KYEISFNVYM FHGGTNFGFM NGATYFGKHS 360
GIVTSYDYDA VLTEAGDYTE KYLKLQKLFQ SVSATPLPRV PKLPPKAVYP PVRPSLYLPL 420
WDALSYLNEP VRSRQPVNME NLPINNGSGQ SYGLVLYEKS ICSGGRLRAH AHDVAQVFLD 480
ETMIGILNEN NKDLHIPELR DCRYLRILVE NQGRVNFSWQ IQNEQKGITG SVSINNSSLE 540
GFTIYSLEMK MSFFERLRSA TWKPVPDSHQ GPAFYCGTLK AGPSPKDTFL SLLNWNYGFV 600
FINGRNLGRY WNIGPQKTLY LPGVWLHPED NEVILFEKMM SGSDIKSTDK PTL 653 
Gene Ontology
 GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR026283; B-gal_1-like.
 IPR008979; Galactose-bd-like.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR001944; Glycoside_Hdrlase_35.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF01301; Glyco_hydro_35 
SMART
  
PROSITE
 PS01182; GLYCOSYL_HYDROL_F35 
PRINTS
 PR00742; GLHYDRLASE35.