UniProt Accession

 NPM3_HUMAN; O75607; Q9UNY6 

Genbank Protein ID

 AY049737; AF081280; AF079325; BC041067; BC054868 

Genbank Nucleotide ID

 AAL12172.1; AAC31609.1; AAD51496.1; AAH41067.1; AAH54868.1 

Protein Name

 Nucleoplasmin-3 

Protein Synonyms/Alias

  

Gene Name

 NPM3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	AVPVANLKLSCQPML	ubiquitination	[1]
125	PPVTFRLKSGSGPVR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May act as a chaperone. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 13 13 Phosphoserine.
 MOD_RES 16 16 Phosphoserine.
 MOD_RES 147 147 Phosphoserine.
 MOD_RES 151 151 Phosphoserine.
 MOD_RES 158 158 Phosphoserine.  

Keyword

 Acetylation; Chaperone; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 178 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006364; P:rRNA processing; IEA:Compara.
 GO:0009303; P:rRNA transcription; IEA:Compara. 

Interpro

 IPR004301; Nucleoplasmin.
 IPR024057; Nucleoplasmin_core_dom. 

Pfam

  

SMART

  

PROSITE

  

PRINTS