UniProt Accession

 RAB9A_HUMAN; P51151; A8K390; Q6ICN1 

Genbank Protein ID

 U44103; AF498944; CR450362; AK290505; CH471074; BC017265 

Genbank Nucleotide ID

 AAC51200.1; AAM21092.1; CAG29358.1; BAF83194.1; EAW98826.1; AAH17265.1 

Protein Name

 Ras-related protein Rab-9A 

Protein Synonyms/Alias

  

Gene Name

 RAB9A 

Gene Synonyms/Alias

 RAB9 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	FQNLSNWKKEFIYYA	ubiquitination	[1]
103	QNLSNWKKEFIYYAD	ubiquitination	[2, 3]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 Involved in the transport of proteins between the endosomes and the trans Golgi network. 

Sequence Annotation

 NP_BIND 14 22 GTP.
 NP_BIND 62 66 GTP (By similarity).
 NP_BIND 124 127 GTP.
 NP_BIND 154 156 GTP.
 MOTIF 36 44 Effector region (By similarity).
 MOD_RES 179 179 Phosphoserine.
 LIPID 200 200 S-geranylgeranyl cysteine (By
 LIPID 201 201 S-geranylgeranyl cysteine (By  

Keyword

 3D-structure; Cell membrane; Complete proteome; Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding; Phosphoprotein; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 201 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005770; C:late endosome; IDA:MGI.
 GO:0005764; C:lysosome; IDA:MGI.
 GO:0045335; C:phagocytic vesicle; IDA:UniProtKB.
 GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0019003; F:GDP binding; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IDA:UniProtKB.
 GO:0003924; F:GTPase activity; IDA:UniProtKB.
 GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.