CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017739
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DnaJ homolog subfamily B member 8 
Protein Synonyms/Alias
  
Gene Name
 DNAJB8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
61EVLSDSKKRSLYDRAacetylation[1]
216VEEDGQLKSVTVNGKacetylation[1]
223KSVTVNGKEQLKWMDacetylation[1]
Reference
 [1] A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
 Hageman J, Rujano MA, van Waarde MA, Kakkar V, Dirks RP, Govorukhina N, Oosterveld-Hut HM, Lubsen NH, Kampinga HH.
 Mol Cell. 2010 Feb 12;37(3):355-69. [PMID: 20159555] 
Functional Description
 Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins. 
Sequence Annotation
 DOMAIN 3 69 J.  
Keyword
 3D-structure; Chaperone; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 232 AA 
Protein Sequence
MANYYEVLGV QASASPEDIK KAYRKLALRW HPDKNPDNKE EAEKKFKLVS EAYEVLSDSK 60
KRSLYDRAGC DSWRAGGGAS TPYHSPFDTG YTFRNPEDIF REFFGGLDPF SFEFWDSPFN 120
SDRGGRGHGL RGAFSAGFGE FPAFMEAFSS FNMLGCSGGS HTTFSSTSFG GSSSGSSGFK 180
SVMSSTEMIN GHKVTTKRIV ENGQERVEVE EDGQLKSVTV NGKEQLKWMD SK 232 
Gene Ontology
  
Interpro
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS. 
Pfam
 PF00226; DnaJ 
SMART
 SM00271; DnaJ 
PROSITE
 PS00636; DNAJ_1
 PS50076; DNAJ_2 
PRINTS
 PR00625; JDOMAIN.