UniProt Accession

 YM71_YEAST; Q05016; D6W051 

Genbank Protein ID

 Z49939; BK006946 

Genbank Nucleotide ID

 CAA90197.1; DAA10125.1 

Protein Name

 Uncharacterized oxidoreductase YMR226C 

Protein Synonyms/Alias

  

Gene Name

 YMR226C; YM9959.08C 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
52	LAARRLEKLEELKKT	acetylation	[1]
58	EKLEELKKTIDQEFP	ubiquitination	[2]
184	AFTDSLRKELINTKI	ubiquitination	[2]
190	RKELINTKIRVILIA	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

  

Sequence Annotation

 NP_BIND 17 44 NAD or NADP (By similarity).
 ACT_SITE 168 168 Proton acceptor (By similarity).
 BINDING 155 155 Substrate (By similarity).
 MOD_RES 260 260 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Oxidoreductase; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 267 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.
 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.
 PR00080; SDRFAMILY.