UniProt Accession

 OLA1_BOVIN; Q2HJ33 

Genbank Protein ID

 BC113336 

Genbank Nucleotide ID

 AAI13337.1 

Protein Name

 Obg-like ATPase 1 

Protein Synonyms/Alias

  

Gene Name

 OLA1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
83	QYHKPASKIPAFLNV	ubiquitination	[1, 2]
216	KEIEVLNKHLFLTSK	ubiquitination	[2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). 

Sequence Annotation

 DOMAIN 24 131 G.
 NP_BIND 32 37 ATP (By similarity).
 MOTIF 267 274 Nuclear export signal (Potential).
 BINDING 231 231 ATP; via carbonyl oxygen (By similarity).
 MOD_RES 294 294 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; ATP-binding; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 396 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0006200; P:ATP catabolic process; IEA:Compara. 

Interpro

 IPR012675; Beta-grasp_dom.
 IPR004396; CHP00092.
 IPR013029; DUF933.
 IPR006073; GTP_binding_domain.
 IPR027417; P-loop_NTPase.
 IPR012676; TGS-like.
 IPR023192; TGS-like_dom. 

Pfam

 PF01926; MMR_HSR1
 PF06071; YchF-GTPase_C 

SMART

  

PROSITE

  

PRINTS

 PR00326; GTP1OBG.