CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035455
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Homeobox protein Nkx-2.1 
Protein Synonyms/Alias
  
Gene Name
 Ttf1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MEGGKFKTHTATacetylation[1]
658AVEDVILKKMSSQELacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 851 AA 
Protein Sequence
MEGGKFKTHT ATLHKKKKWS SVSEKRLQKW PSQHLESEQP QVSVRKKRRR ESQTPAQESL 60
ESEQPWKAKK KKKRRRESQT PAQESLESEQ TPMSMLGKRR RESQTPAQEN LESEQPWKAK 120
KKKRRREYQT PAEESLESEQ PWKAKRKKKK EKESQQLTSS LLKNSETFHK AKKTTAAHKK 180
KKNSVWEVDM ETGIILVDKE NMENLLETSR KDVDIVYVDM SKGQRSAKVN ETEELPMAET 240
QKRDCRELHS DIRSKKNQKH PQKIAPQDAI QGTQPERISL PQSESLSPVD LEGKNTKIAV 300
FCKKKSKKKV FRSQELEAVS ESLVSSETIP ESLDSAHHGG EDETEEEGES IKESHRIRKK 360
SKKKKHKSVT LATSGDSVSV LDSTAESALV DSPEGSGTLR EEDVDHGSTE AEAQARPTEK 420
HRKEIQRLEP THEESNLESA SNSATRCVSE DRRDSDESDV DLGSAVRQLQ EFIPDIQERA 480
ATTIRRMYRD DLGRFKEFKA QGVAIRFGKF SVKENKQIEK NVQDFLSLTG IESADKLLYT 540
DRYPEEKSLI TNLKRKHAFR LHIGKGIARP WKLVYYRAKK IFDVNNYKGR YNEEDTKKLK 600
AYHSLHGNDW KKIGAMVARS SLSVALKFSQ IDGDRNHGTW SKAETQRLIK AVEDVILKKM 660
SSQELRELDS RLQEDPEGRL SIVREKLYKG ISWVEVEARV ETRNWMQCKS KWTEILTKRM 720
THGGFVYRGV KALQAKITLI ERLYELNVND ANEIDWEDLA GAIGDVPPPF VQAKFYKLKA 780
ACVPFWQKKT FPEIIDYLYE NSLPLLKEKL AKKMKKKDSQ IQKPTAPKQN FLFKDIFHCD 840
DDSDEGGLEE P 851 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:Compara.
 GO:0006338; P:chromatin remodeling; IEA:Compara.
 GO:0006363; P:termination of RNA polymerase I transcription; IEA:Compara.
 GO:0006361; P:transcription initiation from RNA polymerase I promoter; IEA:Compara. 
Interpro
 IPR009057; Homeodomain-like.
 IPR017877; Myb-like_dom.
 IPR001005; SANT/Myb. 
Pfam
  
SMART
 SM00717; SANT 
PROSITE
 PS50090; MYB_LIKE 
PRINTS