UniProt Accession

 RS18_MOUSE; P62270; P25232 

Genbank Protein ID

 M76763; M76762; AF100956; AF110520; AK050626; BC081459; BC081458 

Genbank Nucleotide ID

 AAA16795.1; AAA16796.1; AAC69898.1; AAC97978.1; BAC34350.1; AAH81459.1; AAH81458.1 

Protein Name

 40S ribosomal protein S18 

Protein Synonyms/Alias

 Ke-3; Ke3 

Gene Name

 Rps18 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MSLVIPEKFQHILRV	ubiquitination	[1]
54	KADIDLTKRAGELTE	ubiquitination	[1]
78	MQNPRQYKIPDWFLN	ubiquitination	[1]
91	LNRQKDVKDGKYSQV	acetylation	[2]
94	QKDVKDGKYSQVLAN	acetylation	[2]
106	LANGLDNKLREDLER	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 94 94 N6-acetyllysine (By similarity).
 MOD_RES 106 106 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 152 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IBA:RefGenome.
 GO:0015935; C:small ribosomal subunit; IBA:RefGenome.
 GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
 GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
 GO:0006412; P:translation; IBA:RefGenome. 

Interpro

 IPR027437; 30s_Rbsml_prot_S13_C.
 IPR001892; Ribosomal_S13.
 IPR010979; Ribosomal_S13-like_H2TH.
 IPR018269; Ribosomal_S13_CS. 

Pfam

 PF00416; Ribosomal_S13 

SMART

  

PROSITE

 PS00646; RIBOSOMAL_S13_1
 PS50159; RIBOSOMAL_S13_2 

PRINTS