| Tag | Content |
|---|
| CPLM ID | CPLM-011849 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein AHC1 |
Protein Synonyms/Alias | ADA HAT complex component 1 |
Gene Name | AHC1 |
Gene Synonyms/Alias | YOR023C; OR26.13 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 532 | PTDKKPRKAALLTNE | acetylation | [1] | | 548 | EGPDPAAKSSSYYNL | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Functions as component of the transcription regulatory histone acetylation (HAT) complex ADA. ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B. AHC1 is required for the overall structural integrity of the ADA complex. |
Sequence Annotation | MOD_RES 282 282 Phosphoserine.
MOD_RES 505 505 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 566 AA |
Protein Sequence | MMSPAQDKLQ HQHHNPNSSS SSSSKMTNVY QVTTPKSPQD LENNMDEPFK MDTATSNPDK 60
DSENTQRLKY ECAKGEIQNV LNLHIMLNHK HVRHLRRNVQ KVNAKLALLE TLHKDTGLLN 120
KIERTYQLKI KQHQQHSVLG GHFHDSTATE NTNASNYNLS YPVLSDYNIN CQPLSSSSNR 180
NLSTTRIPHH HYHTRSKSNG LLLEPSALRP ANSNIIDYRL TGSKSLSEAI TKPTPVSLPH 240
SNSDGISSPR SSSISPLDEQ PGFQILPFKP SQMHLNHRRN YSSTCLTSNS GIIGKTENNE 300
PIFRRYDGIL VIITCSKCDR SGFTSAQGIV NHTRLKHSKL YSSQPLAVLN NQKLLPNDKQ 360
DPEILSKFKK LNLDPNKDYL PSDIAIPKPQ SPINHSENHT RAPKTVKNTP HLEKLYQNKE 420
DFKKLIDMVN ETPDDLNEYL KQREIQLRYQ KEQEEESSKS DDEASYVPSP SLSATATTTT 480
TTDPPSPPVL SSSLQRKLLR KRKLSLNSST PMEDLPLRER LRANPTDKKP RKAALLTNEL 540
EGPDPAAKSS SYYNLRSKSR LRGSHT 566 |
Gene Ontology | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:SGD. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0016573; P:histone acetylation; IPI:SGD. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
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