| Tag | Content |
|---|
| CPLM ID | CPLM-001592 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | WNT1-inducible-signaling pathway protein 3 |
Protein Synonyms/Alias | WISP-3; CCN family member 6 |
Gene Name | WISP3 |
Gene Synonyms/Alias | CCN6; UNQ462/PRO790/PRO956 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 262 | NCEMRKEKRLCYIQP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Appears to be required for normal postnatal skeletal growth and cartilage homeostasis. |
Sequence Annotation | DOMAIN 44 117 IGFBP N-terminal.
DOMAIN 208 253 TSP type-1.
DOMAIN 268 342 CTCK.
CARBOHYD 178 178 N-linked (GlcNAc...) (Potential).
CARBOHYD 308 308 N-linked (GlcNAc...) (Potential).
DISULFID 268 305 By similarity.
DISULFID 285 319 By similarity.
DISULFID 296 335 By similarity.
DISULFID 299 337 By similarity.
DISULFID 304 341 By similarity. |
Keyword | Alternative splicing; Complete proteome; Disease mutation; Disulfide bond; Glycoprotein; Growth factor; Polymorphism; Reference proteome; Secreted; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 354 AA |
Protein Sequence | MNKRRLLYPS GWLHGPSDMQ GLLFSTLLLA GLAQFCCRVQ GTGPLDTTPE GRPGEVSDAP 60
QRKQFCHWPC KCPQQKPRCP PGVSLVRDGC GCCKICAKQP GEICNEADLC DPHKGLYCDY 120
SVDRPRYETG VCAYLVAVGC EFNQVHYHNG QVFQPNPLFS CLCVSGAIGC TPLFIPKLAG 180
SHCSGAKGGK KSDQSNCSLE PLLQQLSTSY KTMPAYRNLP LIWKKKCLVQ ATKWTPCSRT 240
CGMGISNRVT NENSNCEMRK EKRLCYIQPC DSNILKTIKI PKGKTCQPTF QLSKAEKFVF 300
SGCSSTQSYK PTFCGICLDK RCCIPNKSKM ITIQFDCPNE GSFKWKMLWI TSCVCQRNCR 360
EPGDIFSELK IL 372 |
Gene Ontology | GO:0005615; C:extracellular space; NAS:UniProtKB. GO:0007267; P:cell-cell signaling; TAS:ProtInc. GO:0001558; P:regulation of cell growth; IEA:InterPro. GO:0007165; P:signal transduction; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |