UniProt Accession

 DEK_MOUSE; Q7TNV0; Q80VC5; Q8BZV6 

Genbank Protein ID

 AK033451; BC048844; BC055451 

Genbank Nucleotide ID

 BAC28296.1; AAH48844.1; AAH55451.1 

Protein Name

 Protein DEK 

Protein Synonyms/Alias

  

Gene Name

 Dek 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
336	ELKETVKKLLADANL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in chromatin organization. 

Sequence Annotation

 DOMAIN 153 187 SAP.
 DNA_BIND 342 356 By similarity.
 DNA_BIND 372 376 By similarity.
 MOTIF 209 225 Nuclear localization signal (Potential).
 MOD_RES 20 20 Phosphoserine (By similarity).
 MOD_RES 33 33 Phosphoserine (By similarity).
 MOD_RES 55 55 Phosphoserine (By similarity).
 MOD_RES 163 163 Phosphoserine (By similarity).
 MOD_RES 205 205 Phosphoserine (By similarity).
 MOD_RES 208 208 Phosphoserine (By similarity).
 MOD_RES 214 214 Phosphoserine (By similarity).
 MOD_RES 231 231 Phosphoserine.
 MOD_RES 234 234 Phosphoserine.
 MOD_RES 235 235 Phosphoserine.
 MOD_RES 236 236 Phosphoserine.
 MOD_RES 247 247 Phosphoserine.
 MOD_RES 248 248 Phosphoserine.
 MOD_RES 255 255 Phosphoserine.
 MOD_RES 292 292 Phosphoserine (By similarity).
 MOD_RES 293 293 Phosphoserine (By similarity).
 MOD_RES 294 294 Phosphothreonine (By similarity).
 MOD_RES 295 295 Phosphothreonine (By similarity).
 MOD_RES 301 301 Phosphoserine (By similarity).
 MOD_RES 306 306 Phosphoserine.
 MOD_RES 308 308 Phosphoserine.
 MOD_RES 311 311 Phosphoserine.
 MOD_RES 312 312 Phosphoserine.  

Keyword

 Chromatin regulator; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 380 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
 GO:2001032; P:regulation of double-strand break repair via nonhomologous end joining; IMP:MGI. 

Interpro

 IPR014876; DEK_C.
 IPR009057; Homeodomain-like.
 IPR003034; SAP_dom. 

Pfam

 PF08766; DEK_C
 PF02037; SAP 

SMART

 SM00513; SAP 

PROSITE

 PS50800; SAP 

PRINTS