CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011368
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nicotinamide-nucleotide adenylyltransferase 1 
Protein Synonyms/Alias
 NAD(+) diphosphorylase 1; NAD(+) pyrophosphorylase 1; NMN adenylyltransferase 1 
Gene Name
 NMA1 
Gene Synonyms/Alias
 YLR328W; L8543.16 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
10PTRAPDFKPPSADEEubiquitination[1]
124SETRGVQKYQIADLEubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 MOD_RES 91 91 Phosphoserine.
 MOD_RES 95 95 Phosphoserine.
 MOD_RES 96 96 Phosphoserine.
 MOD_RES 111 111 Phosphoserine.  
Keyword
 ATP-binding; Complete proteome; Direct protein sequencing; NAD; Nucleotide-binding; Nucleotidyltransferase; Phosphoprotein; Pyridine nucleotide biosynthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 401 AA 
Protein Sequence
MDPTRAPDFK PPSADEELIP PPDPESKIPK SIPIIPYVLA DANSSIDAPF NIKRKKKHPK 60
HHHHHHHSRK EGNDKKHQHI PLNQDDFQPL SAEVSSEDDD ADFRSKERYG SDSTTESETR 120
GVQKYQIADL EEVPHGIVRQ ARTLEDYEFP SHRLSKKLLD PNKLPLVIVA CGSFSPITYL 180
HLRMFEMALD AISEQTRFEV IGGYYSPVSD NYQKQGLAPS YHRVRMCELA CERTSSWLMV 240
DAWESLQPSY TRTAKVLDHF NHEINIKRGG VATVTGEKIG VKIMLLAGGD LIESMGEPNV 300
WADADLHHIL GNYGCLIVER TGSDVRSFLL SHDIMYEHRR NILIIKQLIY NDISSTKVRL 360
FIRRAMSVQY LLPNSVIRYI QEHRLYVDQT EPVKQVLGNK E 401 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IDA:SGD.
 GO:0009435; P:NAD biosynthetic process; IDA:SGD. 
Interpro
 IPR004821; Cyt_trans-like.
 IPR005248; NAMN_adtrnsfrase.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF01467; CTP_transf_2 
SMART
  
PROSITE
  
PRINTS