| Tag | Content |
|---|
| CPLM ID | CPLM-038715 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Metabotropic glutamate receptor 5 |
Protein Synonyms/Alias | |
Gene Name | Grm5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 258 | AGEQSFDKLLKKLRS | ubiquitination | [1] | | 827 | KVYIILAKPERNVRS | ubiquitination | [1] | | 889 | VTWAQNEKSTRGQHL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | |
Keyword | Cell membrane; Complete proteome; G-protein coupled receptor; Membrane; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1171 AA |
Protein Sequence | MVLLLILSVL LLKEDVRGSA QSSERRVVAH MPGDIIIGAL FSVHHQPTVD KVHERKCGAV 60
REQYGIQRVE AMLHTLERIN SDPTLLPNIT LGCEIRDSCW HSAVALEQSI EFIRDSLISS 120
EEEEGLVRCV DGSSSFRSKK PIVGVIGPGS SSVAIQVQNL LQLFNIPQIA YSATSMDLSD 180
KTLFKYFMRV VPSDAQQARA MVDIVKRYNW TYVSAVHTEG NYGESGMEAF KDMSAKEGIC 240
IAHSYKIYSN AGEQSFDKLL KKLRSHLPKA RVVACFCEGM TVRGLLMAMR RLGLAGEFLL 300
LGSDGWADRY DVTDGYQREA VGGITIKLQS PDVKWFDDYY LKLRPETNLR NPWFQEFWQH 360
RFQCRLEGFA QENSKYNKTC NSSLTLRTHH VQDSKMGFVI NAIYSMAYGL HNMQMSLCPG 420
YAGLCDAMKP IDGRKLLDSL MKTNFTGVSG DMILFDENGD SPGRYEIMNF KEMGKDYFDY 480
INVGSWDNGE LKMDDDEVWS KKNNIIRSVC SEPCEKGQIK VIRKGEVSCC WTCTPCKENE 540
YVFDEYTCKA CQLGSWPTDD LTGCDLIPVQ YLRWGDPEPI AAVVFACLGL LATLFVTVIF 600
IIYRDTPVVK SSSRELCYII LAGICLGYLC TFCLIAKPKQ IYCYLQRIGI GLSPAMSYSA 660
LVTKTNRIAR ILAGSKKKIC TKKPRFMSAC AQLVIAFILI CIQLGIIVAL FIMEPPDIMH 720
DYPSIREVYL ICNTTNLGVV TPLGYNGLLI LSCTFYAFKT RNVPANFNEA KYIAFTMYTT 780
CIIWLAFVPI YFGSNYKIIT MCFSVSLSAT VALGCMFVPK VYIILAKPER NVRSAFTTST 840
VVRMHVGDGK SSSAASRSSS LVNLWKRRGS SGETLSSNGK SVTWAQNEKS TRGQHLWQRL 900
SVHINKKENP NQTAVIKPFP KSTESRGQGA GAGGGSGPGA AGAGSAGCTA TGGPEPPDAG 960
PKALYDVAEA EERFPAAARP RSPSPISTLS HLAGSAGRTD DDAPSLHSET AARSSSSQGS 1020
LMEQISSVVT RFTANITELN SMMLSTAAAP GPPGTPICSS YLIPKEIQLP TTMTTFAEIQ 1080
PLPAIEVTGG AQPATGPSPA QETPAGAEAA PGKPDLEELV ALTPPSPFRD SVDSGSTTPN 1140
SPVSESALCI PSSPKYDTLI IRDYTQSSSS L 1171 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:MGI. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IDA:MGI. GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. GO:0001639; F:PLC activating G-protein coupled glutamate receptor activity; TAS:MGI. GO:0007612; P:learning; IMP:MGI. GO:0007626; P:locomotory behavior; IMP:MGI. GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |