UniProt Accession

 FITM2_MOUSE; P59266; B9EHX3; Q5BKP7 

Genbank Protein ID

 AK040900; AK043244; AK163611; AL591488; BC090994; BC138522; BC138532 

Genbank Nucleotide ID

 BAC30737.1; BAC31503.1; BAE37420.1; CAM22396.1; AAH90994.1; AAI38523.1; AAI38533.1 

Protein Name

 Fat storage-inducing transmembrane protein 2 

Protein Synonyms/Alias

 Fat-inducing protein 2 

Gene Name

 Fitm2 

Gene Synonyms/Alias

 Fit2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
256	QSCSLTLKRDTYKK*	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization. 

Sequence Annotation

  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 262 AA 

Protein Sequence

Gene Ontology

 GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0035356; P:cellular triglyceride homeostasis; IMP:BHF-UCL.
 GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
 GO:0034389; P:lipid particle organization; IMP:UniProtKB.
 GO:0010890; P:positive regulation of sequestering of triglyceride; IDA:BHF-UCL.
 GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
 GO:0010866; P:regulation of triglyceride biosynthetic process; IMP:BHF-UCL. 

Interpro

 IPR019388; FIT. 

Pfam

 PF10261; Scs3p 

SMART

  

PROSITE

  

PRINTS