CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038233
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 H(+)/Cl(-) exchange transporter 7 
Protein Synonyms/Alias
  
Gene Name
 Clcn7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
59DPPHTFPKEIPHNEKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 783 AA 
Protein Sequence
MQGILTGPLW ESPPETPPPS AEEGPQSHSA LFRIGQMNNV ELDDELLDPE VDPPHTFPKE 60
IPHNEKLLSL KYESLDYDNS ENQLFLEEER RINHTAFRTV EIKRWVICAL IGILTGLVAC 120
FIDIVVENLA GLKYRVIKDN IDKFTEKGGL SFSLLLWATL NSAFVLVGSV IVAFIEPVAA 180
GSGIPQIKCF LNGVKIPHVV RLKTLVIKVS GVILSVVGGL AVGKEGPMIH SGSVIAAGIS 240
QGRSTSLKRD FKIFEYFRRD TEKRDFVSAG AAAGVSAAFG APVGGVLFSL EEGASFWNQF 300
LTWRIFFASM ISTFTLNFVL SIYHGNMWDL SSPGLINFGR FDSEKMAYTI HEIPVFIAMG 360
VVGGILGAVF NALNYWLTMF RIRYIHRPCL QVIEAMLVAA VTATVAFVLI YSSRDCQPLQ 420
GSSMSYPLQL FCADGEYNSM AAAFFNTPEK SVVSLFHDPP GSYNPMTLGL FTLVYFFLAC 480
WTYGLTVSAG VFIPSLLIGA AWGRLFGISL SYLTGAAIWA DPGKYALMGA AAQLGGIVRM 540
TLSLTVIMME ATSNVTYGFP IMLVLMTAKI VGDVFIEGLY DMHIQLQSVP FLHWEAPVTS 600
HSLTAREVMS TPVTCLRRRE KVGIIVDVLS DTASNHNGFP VVEDVGDTQP ARLQGLILRS 660
QLIVLLKHKV FVERSNMGLV QRRLRLKDFR DAYPRFPPIQ SIHVSQDERE CTMDLSEFMN 720
PSPYTVPQEA SLPRVFKLFR ALGLRHLVVV DNHNQVVGLV TRKDLARYRL GKGGLEELSL 780
AQT 783 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro. 
Interpro
 IPR014743; Cl-channel_core.
 IPR001807; Cl-channel_volt-gated.
 IPR002249; Cl_channel-7.
 IPR000644; Cysta_beta_synth_core. 
Pfam
 PF00571; CBS
 PF00654; Voltage_CLC 
SMART
 SM00116; CBS 
PROSITE
 PS51371; CBS 
PRINTS
 PR00762; CLCHANNEL.
 PR01118; CLCHANNEL7.