| Tag | Content |
|---|
| CPLM ID | CPLM-021452 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alpha-1,2-mannosyltransferase ALG9 |
Protein Synonyms/Alias | Asparagine-linked glycosylation protein 9 homolog; Disrupted in bipolar disorder protein 1; Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase |
Gene Name | ALG9 |
Gene Synonyms/Alias | DIBD1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 49 | RTELSGNKAGQVWAP | ubiquitination | [1] | | 63 | PEGSTAFKCLLSARL | ubiquitination | [1] | | 477 | PVNVCVGKEWYRFPS | ubiquitination | [1] | | 539 | SRYIDISKCHYLVDL | ubiquitination | [1] | | 562 | EPKYSSNKEEWISLA | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides. |
Sequence Annotation | CARBOHYD 77 77 N-linked (GlcNAc...) (Potential).
CARBOHYD 593 593 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Chromosomal rearrangement; Complete proteome; Congenital disorder of glycosylation; Disease mutation; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Polymorphism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 611 AA |
Protein Sequence | MASRGARQRL KGSGASSGDT APAADKLREL LGSREAGGAE HRTELSGNKA GQVWAPEGST 60
AFKCLLSARL CAALLSNISD CDETFNYWEP THYLIYGEGF QTWEYSPAYA IRSYAYLLLH 120
AWPAAFHARI LQTNKILVFY FLRCLLAFVS CICELYFYKA VCKKFGLHVS RMMLAFLVLS 180
TGMFCSSSAF LPSSFCMYTT LIAMTGWYMD KTSIAVLGVA AGAILGWPFS AALGLPIAFD 240
LLVMKHRWKS FFHWSLMALI LFLVPVVVID SYYYGKLVIA PLNIVLYNVF TPHGPDLYGT 300
EPWYFYLING FLNFNVAFAL ALLVLPLTSL MEYLLQRFHV QNLGHPYWLT LAPMYIWFII 360
FFIQPHKEER FLFPVYPLIC LCGAVALSAL QHSFLYFQKC YHFVFQRYRL EHYTVTSNWL 420
ALGTVFLFGL LSFSRSVALF RGYHGPLDLY PEFYRIATDP TIHTVPEGRP VNVCVGKEWY 480
RFPSSFLLPD NWQLQFIPSE FRGQLPKPFA EGPLATRIVP TDMNDQNLEE PSRYIDISKC 540
HYLVDLDTMR ETPREPKYSS NKEEWISLAY RPFLDASRSS KLLRAFYVPF LSDQYTVYVN 600
YTILKPRKAK QIRKKSGG 618 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro. GO:0052926; F:dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; IEA:EC. GO:0052918; F:dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; IEA:EC. GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome. GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro. GO:0043687; P:post-translational protein modification; TAS:Reactome. GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |