CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020532
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RWD domain-containing protein 1 
Protein Synonyms/Alias
 DRG family-regulatory protein 2; IH1 
Gene Name
 Rwdd1 
Gene Synonyms/Alias
 Dfrp2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
119NEIVDQIKTRREEEKubiquitination[1]
157NFLSWKAKFDAELLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Protects DRG2 from proteolytic degradation. 
Sequence Annotation
 DOMAIN 10 114 RWD.
 REGION 142 197 Interaction with DRG2.
 MOD_RES 144 144 Phosphothreonine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MTDYGEEQRN ELEALESIYP DSFTVLSESP PSFTITVTSE AGENDETVQT TLKFTYSEKY 60
PDETPLYEIF SQENLEDNDV SDILKLLALQ AEENLGMVMI FTLVTAVQEK LNEIVDQIKT 120
RREEEKKQKE KEAEEAEKKL FHGTPVTIEN FLSWKAKFDA ELLEIKKKRM KEEEQAGKNK 180
LSGKQLFETD HNLDTSDIQF LEDAGNNVEV DESLFQEMDD LELEDGEDDP DYNPVAPGSD 240
SSD 243 
Gene Ontology
  
Interpro
 IPR006575; RWD-domain.
 IPR016135; UBQ-conjugating_enzyme/RWD. 
Pfam
 PF05773; RWD 
SMART
 SM00591; RWD 
PROSITE
 PS50908; RWD 
PRINTS