CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026157
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinyl-CoA ligase [ADP-forming] subunit beta 
Protein Synonyms/Alias
 Succinyl-CoA synthetase subunit beta 
Gene Name
 sucC 
Gene Synonyms/Alias
 TTHA0538 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
36GVPVPPGKVAYTPEEacetylation[1]
45AYTPEEAKRIAEEFGacetylation[1]
84TPQEAYEKAQAILGMacetylation[1]
362GTAEEEAKKLLEGKPacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
  
Sequence Annotation
 DOMAIN 22 248 ATP-grasp (By similarity).
 NP_BIND 48 113 ATP (By similarity).
 METAL 201 201 Magnesium or manganese (By similarity).
 METAL 203 203 Magnesium or manganese (By similarity).  
Keyword
 ATP-binding; Complete proteome; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Reference proteome; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 391 AA 
Protein Sequence
MPLTGVARQG RWVLNLHEYQ AKEILARYGV PVPPGKVAYT PEEAKRIAEE FGKRVVIKAQ 60
VHVGGRGKAG GVKLADTPQE AYEKAQAILG MNIKGLTVKK VLVAEAVDIA KEYYAGLILD 120
RAKKRVVLML SKEGGVDIEE VAAERPEAIH KFWIDPHKGF RPFEAREMVK RAGLEGNLNK 180
LAQVLVALYR AYEGVDASIA EINPLVVTTD GGIVAADAKI VLDDNALFRH PDLAELREVE 240
AEHPLEVEAS NYGFAYVKLD GNIGIIGNGA GLVMYTLDLV NRVGGKPANF LDIGGGAKAD 300
VVYNALKVVL KDPDVKGVFI NIFGGITRAD EVAKGVIRAL EEGLLTKPVV MRVAGTAEEE 360
AKKLLEGKPV YMYPTSIEAA KVIVAMVGGA A 391 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0030145; F:manganese ion binding; IEA:HAMAP.
 GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:HAMAP.
 GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS