UniProt Accession

 PSPE_ECOLI; P23857 

Genbank Protein ID

 X57560; U00096; AP009048 

Genbank Nucleotide ID

 CAA40793.1; AAC74390.1; BAA14877.1 

Protein Name

 Thiosulfate sulfurtransferase PspE 

Protein Synonyms/Alias

 TST; Phage shock protein E 

Gene Name

 pspE 

Gene Synonyms/Alias

 b1308; JW1301 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
77	GRQSGQAKEILSEMG	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspE catalyzes the sulfur-transfer reaction from thiosulfate to cyanide, to form sulfite and thiocyanate. Also able to use dithiol (dithiothreitol) as an alternate sulfur acceptor. Also possesses a very low mercaptopyruvate sulfurtransferase activity. 

Sequence Annotation

 DOMAIN 20 104 Rhodanese.
 ACT_SITE 67 67 Cysteine persulfide intermediate.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Periplasm; Reference proteome; Signal; Stress response; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 104 AA 

Protein Sequence

Gene Ontology

 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
 GO:0004792; F:thiosulfate sulfurtransferase activity; IDA:EcoCyc.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 

Interpro

 IPR014323; Phageshock_PspE.
 IPR001763; Rhodanese-like_dom. 

Pfam

 PF00581; Rhodanese 

SMART

 SM00450; RHOD 

PROSITE

 PS50206; RHODANESE_3 

PRINTS