| Tag | Content |
|---|
| CPLM ID | CPLM-001344 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein Wiz |
Protein Synonyms/Alias | Widely-interspaced zinc finger-containing protein |
Gene Name | Wiz |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1630 | VGNIYTLKCRFCEVE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization. |
Sequence Annotation | ZN_FING 308 330 C2H2-type 1.
ZN_FING 345 367 C2H2-type 2.
ZN_FING 454 477 C2H2-type 3.
ZN_FING 734 756 C2H2-type 4.
ZN_FING 802 824 C2H2-type 5.
ZN_FING 903 925 C2H2-type 6.
ZN_FING 1076 1098 C2H2-type 7.
ZN_FING 1260 1282 C2H2-type 8.
ZN_FING 1430 1452 C2H2-type 9.
ZN_FING 1629 1655 C2H2-type 10.
REGION 1063 1067 Interaction with CTBP1 and CTBP2 1.
REGION 1247 1251 Interaction with CTBP1 and CTBP2 2.
MOD_RES 1029 1029 Phosphoserine (By similarity).
MOD_RES 1031 1031 Phosphothreonine (By similarity).
MOD_RES 1039 1039 Phosphoserine (By similarity).
MOD_RES 1045 1045 Phosphoserine.
MOD_RES 1049 1049 Phosphothreonine.
MOD_RES 1050 1050 Phosphoserine.
MOD_RES 1112 1112 Phosphoserine (By similarity).
MOD_RES 1160 1160 Phosphoserine (By similarity).
MOD_RES 1167 1167 Phosphoserine (By similarity).
MOD_RES 1179 1179 Phosphoserine (By similarity).
MOD_RES 1184 1184 Phosphoserine (By similarity).
MOD_RES 1195 1195 N6,N6,N6-trimethyllysine; by EHMT2;
MOD_RES 1195 1195 N6,N6-dimethyllysine; by EHMT2; alternate
MOD_RES 1296 1296 Phosphoserine (By similarity).
MOD_RES 1342 1342 Phosphoserine (By similarity).
MOD_RES 1347 1347 Phosphoserine (By similarity).
MOD_RES 1550 1550 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1684 AA |
Protein Sequence | MEGLLAGGLA APDHPRGPAP REDIESGAEA AEGEGDIFPS SHYLPITKEG PRDILDGRSG 60
ISDGQPHPGL SEALPRATSA THRISSCYWD GDSLDFQPGS PPPHLLGPFP ASLDVQGSWE 120
HPMVQEAREG TPSEQRFKDS VIVRTMKPYA KLKGSRKFLH HQGEVKFLEK YSPSHHKFDW 180
LQDTDEQGPL KDTGLHLDLP AQPPTVTSFR RVIVPVDNTP KTLDMEVMGT REDLEDFGQV 240
AQPSEWGLHT SASEVATQTW TVNSEASVER LQPLLSPVQT GPYLCELLQE VAGGVDSNEE 300
EEEEPAVFPC IECSIYFKHK EHLLEHMSQH RRAPGQEPPA DLAPLACSEC GWAFTEPTAL 360
EQHWQLHQAS REKIIEEIQK LKQFPGDEGR EARLQCSKCV FGTNSSRAFM QHAKLHVRGS 420
LPSRQATEPF RGGSPVLDVS TLVYPSYGDS SGLNTCVHCG FTAPSKSLLR EHTRLVHAHH 480
AHWEEVGEAF EDLTSQPCTS QDAYTHSPDT ATVDYFSKSE PLLASVWQEN PSGYDPDLAF 540
GPDYQQPGMR NFPLLNSGQQ SLGKLAFPSP MASASYSIQR NRNKSTVHLQ RMEDKSHLWS 600
EEEEEEDEDV VLTSERDFTP ENGAFPPLAI PSLIPQPALE LKQTFQDALQ AVDASETQQQ 660
QLQGMVPIVL MAKLRPQVIA ATTRASPQLP PEEPELRSTH PLDFLLLDAP LGGSLGLNTL 720
LEGDPAMALK HEERKCPYCP DRFHYGIGLA NHVRGHLNRV GVSYNVRHFI SAEEVKAIER 780
RFSFQKKKKK VANFDPGTFS LMRCDFCGAG FDTRAGLSSH ARAHLRDFGI TNWELTISPI 840
NILQELLATS AAELPPSPLG REPGGPPRSF LTSRRPRLPL TMPFPPTWAE DPGPIYGDAQ 900
SLTTCEVCGA CFETRKGLSS HARSHLRQLG VAESESSGAP IDLLYELVKQ KGLPDAPLGL 960
TPSLTKKSNS PKEFLAGAAR PGLLTLAKPM DAPAVNKAIK SPPGFSAKGL THPSSSPLLK 1020
KAPLTLAGSP TPKNPEDKSP QLSLSPRPTS PKAQWPQSED EGPLNLTSGP EPTRDIRCEF 1080
CGEFFENRKG LSSHARSHLR QMGVTEWYVN GSPIDTLREI LKRRTQSRPG GHLHPPGPSP 1140
KALAKVLSTG GPGSSLEARS PSDLHISPLT KKLPPPPGSP LGHSPTASPP PTARKMFSGL 1200
ATPSLPKKLK PEHMRVEIKR EMLPGTLHGE PHPSEGPWGT PREDMAPLNL SARAEPVRDI 1260
RCEFCGEFFE NRKGLSSHAR SHLRQMGVTE WSVNGSPIDT LREILKKKSK LCLIKKEPPA 1320
GDLAPALTED GSPTAAPGAL HSPLPLSPLA SRPGKPGAGP TQVPRELSLS PITGSKPSAA 1380
SYLGPVATKR PLQEDRFLPA EVKAKTYIQT ELPFKAKTLH EKTSHSSTEA CCELCGLYFE 1440
NRKALASHAR AHLRQFGVTE WCVNGSPIET LSEWIKHRPQ KVGAYRSYIQ GGRPFTKKFR 1500
SAGHGRDSDK RPPLGLAPGG LSLVGRSAGG EPGLEAGRAA DSGERPLATS PPGTVKSEEH 1560
QRQNINKFER RQARPSDASA ARGGEEVNDL QQKLEEVRQP PPRVRPVPSL VPRPPQTSLV 1620
KFVGNIYTLK CRFCEVEFQG PLSIQEEWVR HLQRHILEMN FSKADPPPEE PQAPQAQTAA 1680
VEAP 1684 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |