UniProt Accession

 G3V6I5_RAT; G3V6I5 

Genbank Protein ID

 AABR06062859; CH474017 

Genbank Nucleotide ID

 EDL96290.1 

Protein Name

 Protein Dnaja3 

Protein Synonyms/Alias

 RCG49803, isoform CRA_a 

Gene Name

 Dnaja3 

Gene Synonyms/Alias

 rCG_49803 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
134	DDPKAKEKFSQLAEA	acetylation	[1]
385	AGIQTDQKIRLTGKG	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Chaperone; Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 480 AA 

Protein Sequence

Gene Ontology

 GO:0005884; C:actin filament; IEA:Compara.
 GO:0019897; C:extrinsic to plasma membrane; IEA:Compara.
 GO:0033256; C:I-kappaB/NF-kappaB complex; IEA:Compara.
 GO:0008385; C:IkappaB kinase complex; IEA:Compara.
 GO:0042645; C:mitochondrial nucleoid; IEA:Compara.
 GO:0031594; C:neuromuscular junction; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0045211; C:postsynaptic membrane; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005083; F:small GTPase regulator activity; IEA:Compara.
 GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0006924; P:activation-induced cell death of T cells; IEA:Compara.
 GO:0007569; P:cell aging; IEA:Compara.
 GO:0009790; P:embryo development; IEA:Compara.
 GO:0006264; P:mitochondrial DNA replication; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
 GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; IEA:Compara.
 GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0006469; P:negative regulation of protein kinase activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0031398; P:positive regulation of protein ubiquitination; IEA:Compara.
 GO:0042102; P:positive regulation of T cell proliferation; IEA:Compara.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0050821; P:protein stabilization; IEA:Compara.
 GO:0009408; P:response to heat; IEA:InterPro.
 GO:0034341; P:response to interferon-gamma; IEA:Compara.
 GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:Compara.
 GO:0033077; P:T cell differentiation in thymus; IEA:Compara. 

Interpro

 IPR012724; DnaJ.
 IPR002939; DnaJ_C.
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS.
 IPR008971; HSP40/DnaJ_pept-bd.
 IPR001305; HSP_DnaJ_Cys-rich_dom. 

Pfam

 PF00226; DnaJ
 PF01556; DnaJ_C
 PF00684; DnaJ_CXXCXGXG 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2
 PS51188; ZF_CR 

PRINTS

 PR00625; JDOMAIN.