CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034502
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RAD18 
Protein Synonyms/Alias
  
Gene Name
 Rad18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
318RMRLEASKLNENVMVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 449 AA 
Protein Sequence
MEVLAEPRWP PGLAVMKTID DLLRCGICFE YFNIAVIIPQ CSHNYCSLCI RKFLSYKTQC 60
PTCCVAVTEP DLRNNRLLDE LVKSMNFART HLLQFALESP PISPVSSTSK KVVVKVHNAD 120
AAQHPVKQAN RLMDKFLIRE TGDCVFELLG KENERKFSPQ KELSTSAEIK ETSLLGKPVL 180
GLSDANGPVT PSTSTMKLDT KVSCPVCGVS IPENHINKHL DSCLSREEKK ESLRSSAHKR 240
KPLPKTVYNL LSDRDLKKKL KQYGLSVQGN KQQLIKRHQE FVHMYNAQCD ALHPKSAAEI 300
VQEIESMEKT RMRLEASKLN ENVMVFTKNQ TEKEIEEVHS EYPQEDNVSF SDTVSVTNHF 360
PQPQLDSPGP SEPERPDDSS SCTDILFSSD SDSCNSSSSD IIRDLLEEEE AWEAAHKNDQ 420
NREVSPQQTR RTRASECVEI EPRNKRNKN 449 
Gene Ontology
 GO:0000785; C:chromatin; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0001741; C:XY body; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.
 GO:0006974; P:response to DNA damage stimulus; IMP:MGI.
 GO:0009411; P:response to UV; IMP:MGI.
 GO:0007283; P:spermatogenesis; IMP:MGI. 
Interpro
 IPR003034; SAP_dom.
 IPR006642; Znf_Rad18_put.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF02037; SAP 
SMART
 SM00184; RING
 SM00513; SAP
 SM00734; ZnF_Rad18 
PROSITE
 PS50800; SAP
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS