CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003304
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heme exporter protein C 
Protein Synonyms/Alias
 Cytochrome c-type biogenesis protein CcmC 
Gene Name
 ccmC 
Gene Synonyms/Alias
 yejT; yejU; b2199; JW2187 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
230NLILLMEKRRPWVSEacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. 
Sequence Annotation
  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Cytochrome c-type biogenesis; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 245 AA 
Protein Sequence
MWKTLHQLAI PPRLYQICGW FIPWLAIASV VVLTVGWIWG FGFAPADYQQ GNSYRIIYLH 60
VPAAIWSMGI YASMAVAAFI GLVWQMKMAN LAVAAMAPIG AVFTFIALVT GSAWGKPMWG 120
TWWVWDARLT SELVLLFLYV GVIALWHAFD DRRLAGRAAG ILVLIGVVNL PIIHYSVEWW 180
NTLHQGSTRM QQSIDPAMRS PLRWSIFGFL LLSATLTLMR MRNLILLMEK RRPWVSELIL 240
KRGRK 245 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0050662; F:coenzyme binding; IPI:EcoCyc.
 GO:0015232; F:heme transporter activity; IEA:InterPro.
 GO:0017004; P:cytochrome complex assembly; IMP:EcoCyc.
 GO:0008535; P:respiratory chain complex IV assembly; IEA:InterPro. 
Interpro
 IPR002541; Cyt_c_assembly.
 IPR003557; Cyt_c_biogenesis_CcmC. 
Pfam
 PF01578; Cytochrom_C_asm 
SMART
  
PROSITE
  
PRINTS
 PR01386; CCMCBIOGNSIS.