UniProt Accession

 H0Y861_HUMAN; H0Y861 

Genbank Protein ID

 AL663123 

Genbank Nucleotide ID

  

Protein Name

 Transmembrane protein 222 

Protein Synonyms/Alias

  

Gene Name

 TMEM222 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
6	**AETDMKQYQGSGG	ubiquitination	[1]
72	EDNMAFGKPAKYWKL	ubiquitination	[1, 2]
75	MAFGKPAKYWKLDPA	ubiquitination	[2]
78	GKPAKYWKLDPAQVY	ubiquitination	[1]
104	HDASEEYKHRMHNLC	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 158 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR008496; DUF778. 

Pfam

 PF05608; DUF778 

SMART

  

PROSITE

  

PRINTS