| Tag | Content |
|---|
| CPLM ID | CPLM-016621 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 38 |
Protein Synonyms/Alias | Deubiquitinating enzyme 38; Ubiquitin thioesterase 38; Ubiquitin-specific-processing protease 38 |
Gene Name | Usp38 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 541 | DRLHEEEKILRVQSS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked Ubiquitin chains (By similarity). |
Sequence Annotation | ACT_SITE 454 454 Nucleophile (By similarity).
ACT_SITE 857 857 Proton acceptor (By similarity). |
Keyword | Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1042 AA |
Protein Sequence | MDKILEGLVS SSHPLPLKRM IVRKVVEFAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYHSVDRKD VAILDYIHNG LKLIMSCPSV 120
LDLFSLLQVE VLRMVCERPE PVLCARLSDL LTDFVQCVPK GKLSVTFCQQ LVRTIGHFQC 180
VSTQEKELRE YVSQVTKVST LLQNIWKAEP STLLPSLQEV FASISSTDAS FEPSVALASL 240
VQHIPLQMIT VLIRSLTTDP NVKDASMTQA LCRMIDWLSW PLAQHVDTWV IALLKGLAAV 300
QKFTILIDVT LLKIELVFNR LWFPLVRPGA LAVLSHMLLS FQHSPEAFHV IVPHIVNLVH 360
SFRSDGLPSS TAFLVQLTEL VHCMMYHYSG FPDLYEPILE AVKDFPKPSE EKIKLILNQS 420
AWTSQSNALA SCLSRLSGKS ETGKTGLINL GNTCYMNSVL QALFMATEFR RQVLSLNLNG 480
CNSLMKKLQH LFAFLAHTQR EAYAPRIFFE ASRPPWFTPR SQQDCSEYLR FLLDRLHEEE 540
KILRVQSSHK PSEGLDCAET CLQEVTSKVA VPTESPGTGD SEKTLIEKMF GGKLRTHICC 600
LNCGSTSHKV EAFTDLSLAF CPSPSVEDLS FQDTASLPSA QDDGLMQTSV ADPEEEPVVY 660
NPATAAFVCD SVVNQRVLGS PPVEFHCAES SSVPEESAKI LISKDVPQNP GGESTTSVTD 720
LLNYFLAPEV LTGENQYYCE SCASLQNAEK TMQITEEPEY LILTLLRFSY DQKYHVRRKI 780
LDNVSLPLVL ELPVKRTASF SSLSQSWSVD VDFTDINENL PKKLKPSGTE EAFCPKLVPY 840
LLSSVVVHSG VSSESGHYYS YARNITGTES SYQMCPQSES LALAPSQSCL LGVESPNTVI 900
EQDLENKEMS QEWFLFNDSR VTFTSFQSVQ KITSRFPKDT AYVLLYKKQS RANGIDSDNP 960
ASGVWANGDP PLQKELMDAI TKDNKLYLQE QELNARARAL QAASASCSFR PNGFDDNDPP 1020
GSCGPTGGGG GGGFNTVGRL VF 1042 |
Gene Ontology | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |