CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017880
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA-binding protein 12 
Protein Synonyms/Alias
 RNA-binding motif protein 12; SH3/WW domain anchor protein in the nucleus; SWAN 
Gene Name
 Rbm12 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
444LPFEAENKHVIDFFKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 304 379 RRM 1.
 DOMAIN 430 507 RRM 2.
 DOMAIN 916 992 RRM 3.
 MOD_RES 420 420 Phosphoserine (By similarity).
 MOD_RES 422 422 Phosphoserine.
 MOD_RES 424 424 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 992 AA 
Protein Sequence
MAVVIRLQGL PIVAGTMDIR HFFSGLTIPD GGVHIVGGEL GEAFIVFATD EDARLGMMRT 60
GGTIKGSKVT LLLSSKTEMQ NMIELSRRRF ETANLDIPPA NASRSGPPPS SGMSSRVNLP 120
AIVPNFNNPS PSVVTATTSV HESNKNIQTF STASVGTAPP SMGTSFGSPT FSSTIPSTAS 180
PMNTVPPPPI PPIPAMPSLP PLPSIPPIPV PPPVPTLPPV PPVPPIPPVP SVPPMTTLPP 240
MSGMPPLNPP PVAPLPAGMN GSGAPIGLNN NMNPVFLGPL NPVNSIQMNS QSSVKSLPIN 300
PDDLYVSVHG MPFSAMENDV REFFHGLRVD AVHLLKDHVG RNNGNGLVKF LSPQDTFEAL 360
KRNRMLMIQR YVEVSPATER QWVAAGGHIT FKQSMGPSGQ AHPPPQTLPR SKSPSGQKRS 420
RSRSPHEAGF CVYLKGLPFE AENKHVIDFF KKLDIVEDSI YIAYGPNGKA TGEGFVEFRN 480
DADYKAALCR HKQYMGNRFI QVHPITKKGM LEKIDMIRKR LQNFSYDQRE LVLNPEGEVS 540
SAKVCAHITN IPFSITKMDV LQFLEGIPVD ESAVHVLVDN NGQGLGQALV QFKTEDDAHK 600
SEHLHRKKLN GREAFVHIVT LEDMREIEKN PPAQGKKGLK ISVPGNPAVP VIPSAGMPAA 660
GIPTAGIPGA GLPSAGMPGA GMPSSGMPGP GMPGPGIPGA GIPGPAMPGP AMPGPAMPGP 720
AMPGPAMPGP AMPGPAMPGP AMPGPAIPGP AIPGPAIPGA GIPSAGGEEH VFLTVGSKEA 780
NNGPPFNFPG NFGGPNAFGP PLPPPGLGGA FGDVRPVMPS VGNSGLPGLG LEVPGFGGAP 840
NNISGPSGFG GIPQNFGNGP GSLNAPPGFG SGPPGLGSVP GHLSGPPAFG PGPGPGPIHI 900
GGPPGFGASS GKPGPTIIKV QNMPFTVSID EILDFFYGYQ VIPGSVCLKY NEKGMPTGEA 960
MVAFESRDEA TAAVIDLNDR PIGSRKVKLV LG 992 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS