UniProt Accession

 F8W7F7_HUMAN; F8W7F7 

Genbank Protein ID

 AC004938 

Genbank Nucleotide ID

  

Protein Name

 Transmembrane emp24 domain-containing protein 4 

Protein Synonyms/Alias

  

Gene Name

 TMED4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
63	YRTQMWDKQKEVFLP	ubiquitination	[1]
65	TQMWDKQKEVFLPST	ubiquitination	[1]
82	LGMHVEVKDPDGKVV	ubiquitination	[1]
169	IWQMRHLKSFFEAKK	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 178 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006810; P:transport; IEA:InterPro. 

Interpro

 IPR009038; GOLD. 

Pfam

 PF01105; EMP24_GP25L 

SMART

  

PROSITE

 PS50866; GOLD 

PRINTS