UniProt Accession

 RNS11_HUMAN; Q8TAA1 

Genbank Protein ID

 BX161458; AK098687; AY358794; BC025410 

Genbank Nucleotide ID

 CAD61920.1; BAC05378.1; AAQ89154.1; AAH25410.1 

Protein Name

 Probable ribonuclease 11 

Protein Synonyms/Alias

 RNase 11 

Gene Name

 RNASE11 

Gene Synonyms/Alias

 C14orf6; UNQ5832/PRO19669 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
87	SLHYNDPKGNSSGND	ubiquitination	[1]
95	GNSSGNDKECCNDMT	ubiquitination	[1]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

 REGION 115 119 Substrate binding (By similarity).
 ACT_SITE 82 82 Proton acceptor (By similarity).
 DISULFID 98 158 By similarity.
 DISULFID 114 169 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Endonuclease; Hydrolase; Nuclease; Polymorphism; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 199 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0004522; F:pancreatic ribonuclease activity; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 

Interpro

 IPR001427; RNaseA.
 IPR023412; RNaseA_domain. 

Pfam

 PF00074; RnaseA 

SMART

  

PROSITE

  

PRINTS