| Tag | Content |
|---|
| CPLM ID | CPLM-003224 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribosomal large subunit pseudouridine synthase A |
Protein Synonyms/Alias | 23S rRNA pseudouridine(746) synthase; rRNA pseudouridylate synthase A; rRNA-uridine isomerase A; tRNA pseudouridine(32) synthase |
Gene Name | rluA |
Gene Synonyms/Alias | yabO; b0058; JW0057 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 133 | KVCYETGKPAQTEYE | acetylation | [1] | | 155 | NTARVVLKPITGRSH | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Responsible for synthesis of pseudouridine from uracil- 746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs. |
Sequence Annotation | ACT_SITE 64 64 |
Keyword | 3D-structure; Complete proteome; Direct protein sequencing; Isomerase; Reference proteome; rRNA processing; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 219 AA |
Protein Sequence | MGMENYNPPQ EPWLVILYQD DHIMVVNKPS GLLSVPGRLE EHKDSVMTRI QRDYPQAESV 60
HRLDMATSGV IVVALTKAAE RELKRQFRER EPKKQYVARV WGHPSPAEGL VDLPLICDWP 120
NRPKQKVCYE TGKPAQTEYE VVEYAADNTA RVVLKPITGR SHQLRVHMLA LGHPILGDRF 180
YASPEARAMA PRLLLHAEML TITHPAYGNS MTFKAPADF 219 |
Gene Ontology | GO:0009982; F:pseudouridine synthase activity; IDA:EcoCyc. GO:0003723; F:RNA binding; IEA:InterPro. GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IMP:EcoCyc. GO:0031119; P:tRNA pseudouridine synthesis; IMP:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |