CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029558
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AlphaB-crystallin 
Protein Synonyms/Alias
 Uncharacterized protein 
Gene Name
 Cryab 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
174PAVTAAPKK******acetylation[1]
175AVTAAPKK*******acetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 175 AA 
Protein Sequence
MDIAIHHPWF RRPFFSFPSP SRLFDQFFGE HLLESELFPT STSLSPFYLR PPSFLRLPSW 60
ADTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR 120
KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSVPERTIP ITREEKPAVT AAPKK 175 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0005212; F:structural constituent of eye lens; IEA:InterPro.
 GO:0060561; P:apoptotic process involved in morphogenesis; IEA:Compara.
 GO:0002088; P:lens development in camera-type eye; IEA:Compara.
 GO:0007517; P:muscle organ development; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0010629; P:negative regulation of gene expression; IEA:Compara.
 GO:0032387; P:negative regulation of intracellular transport; IEA:Compara.
 GO:0051260; P:protein homooligomerization; IEA:Compara.
 GO:0042542; P:response to hydrogen peroxide; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0007021; P:tubulin complex assembly; IEA:Compara. 
Interpro
 IPR002068; a-crystallin/Hsp20_dom.
 IPR001436; Alpha-crystallin/HSP.
 IPR012273; Alpha-crystallin_B.
 IPR003090; Alpha-crystallin_N.
 IPR008978; HSP20-like_chaperone. 
Pfam
 PF00525; Crystallin
 PF00011; HSP20 
SMART
  
PROSITE
 PS01031; HSP20 
PRINTS
 PR00299; ACRYSTALLIN.