CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041662
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transketolase 
Protein Synonyms/Alias
 Transketolase, isoform CRA_a 
Gene Name
 Tkt 
Gene Synonyms/Alias
 rCG_42377 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
38RAMEGYHKPDQQKLQacetylation[1]
43YHKPDQQKLQALKDTacetylation[1]
48QQKLQALKDTANRLRacetylation[1]
91FFHTMRYKALDPRNPacetylation[1]
236HQVDVYQKRCEAFGWacetylation[1]
264CKAFGQAKHQPTAIIacetylation[1]
273QPTAIIAKTFKGRGIacetylation[1]
286GITGIEDKEAWHGKPacetylation[1]
286GITGIEDKEAWHGKPubiquitination[2]
292DKEAWHGKPLPKNMAacetylation[1]
313IYSQVQSKKKILATPacetylation[1]
315SQVQSKKKILATPPQubiquitination[2]
342MPTPPNYKVGDKIATacetylation[1]
346PNYKVGDKIATRKAYacetylation[1]
351GDKIATRKAYGLALAacetylation[1]
359AYGLALAKLGHASDRacetylation[1]
384STFSELFKKEHPDRFacetylation[1]
385TFSELFKKEHPDRFIacetylation[1]
531AKVVLKSKDDQVTVIacetylation[1]
555LAAAEMLKKEKIGVRacetylation[1]
570VLDPFTIKPLDKKLIacetylation[1]
574FTIKPLDKKLILDCAacetylation[1]
629SQVPRSGKPAELLKMacetylation[1]
635GKPAELLKMFGIDKDacetylation[1]
641LKMFGIDKDAIVQAVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 655 AA 
Protein Sequence
MDPVRQIQCD REGKRFPFLS APPASTSSPD RAMEGYHKPD QQKLQALKDT ANRLRISSIQ 60
ATTAAGSGHP TSCCSAAEIM AVLFFHTMRY KALDPRNPHN DRFVLSKGHA APILYAVWAE 120
AGFLPEAELL NLRKISSDLD GHPVPKQAFT DVATGSLGQG LGAACGMAYT GKYFDKASYR 180
VYCMLGDGEV SEGSVWEAMA FAGIYKLDNL VAIFDINRLG QSDPAPLQHQ VDVYQKRCEA 240
FGWHAIIVDG HSVEELCKAF GQAKHQPTAI IAKTFKGRGI TGIEDKEAWH GKPLPKNMAE 300
QIIQEIYSQV QSKKKILATP PQEDAPSVDI ANIRMPTPPN YKVGDKIATR KAYGLALAKL 360
GHASDRIIAL DGDTKNSTFS ELFKKEHPDR FIECYIAEQN MVSIAVGCAT RDRTVPFCST 420
FAAFFTRAFD QIRMAAISES NINLCGSHCG VSIGEDGPSQ MALEDLAMFR SVPMSTVFYP 480
SDGVATEKAV ELAANTKGIC FIRTSRPENA IIYSNNEDFQ VGQAKVVLKS KDDQVTVIGA 540
GVTLHEALAA AEMLKKEKIG VRVLDPFTIK PLDKKLILDC ARATKGRILT VEDHYYEGGI 600
GEAVSAAVVG EPGVTVTRLA VSQVPRSGKP AELLKMFGID KDAIVQAVKG LVTKG 655 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR009014; Transketo_C/Pyr-ferredox_oxred.
 IPR015941; Transketolase-like_C.
 IPR005475; Transketolase-like_Pyr-bd.
 IPR020826; Transketolase_BS.
 IPR005476; Transketolase_C.
 IPR005474; Transketolase_N. 
Pfam
 PF02779; Transket_pyr
 PF02780; Transketolase_C
 PF00456; Transketolase_N 
SMART
 SM00861; Transket_pyr 
PROSITE
 PS00801; TRANSKETOLASE_1
 PS00802; TRANSKETOLASE_2 
PRINTS