CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009349
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fibroblast growth factor 12 
Protein Synonyms/Alias
 FGF-12; Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor 
Gene Name
 Fgf12 
Gene Synonyms/Alias
 Fhf1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
4****MESKEPQLKGIubiquitination[1]
9ESKEPQLKGIVTRLFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probably involved in nervous system development and function. 
Sequence Annotation
 MOTIF 11 38 Bipartite nuclear localization signal  
Keyword
 Alternative splicing; Complete proteome; Growth factor; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK 60
ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ 120
IMKGNRVKKT KPSSHFVPKP IEVCMYREPS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS 180
T 181 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008201; F:heparin binding; IEA:Compara.
 GO:0008344; P:adult locomotory behavior; IGI:MGI.
 GO:0007254; P:JNK cascade; IEA:Compara.
 GO:2001258; P:negative regulation of cation channel activity; IEA:Compara.
 GO:0050905; P:neuromuscular process; IGI:MGI.
 GO:0010765; P:positive regulation of sodium ion transport; IGI:MGI.
 GO:0007268; P:synaptic transmission; IGI:MGI. 
Interpro
 IPR008996; Cytokine_IL1-like.
 IPR002209; GF_heparin-bd.
 IPR002348; IL1_HBGF. 
Pfam
 PF00167; FGF 
SMART
 SM00442; FGF 
PROSITE
 PS00247; HBGF_FGF 
PRINTS
 PR00263; HBGFFGF.
 PR00262; IL1HBGF.