Tag | Content |
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CPLM ID | CPLM-030807 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ryanodine receptor 2 |
Protein Synonyms/Alias | cDNA FLJ54506, highly similar to Ryanodine receptor 2 |
Gene Name | RYR2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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252 | IDEGAWMKRLAVFSQ | ubiquitination | [1] |
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Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Receptor; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1421 AA |
Protein Sequence | MKTGLESVKS ALRAFLDNAA EDLEKTMENL KQGQFTHTRN QPKGVTQIIN YTTVALLPML 60 SSLFEHIGQH QFGEDLILED VQVSCYRILT SLYALGTSKS IYVERQRSAL GECLAAFAGA 120 FPVAFLETHL DKHNIYSIYN TKSSRERAAL SLPTNVEDVC PNIPSLEKLM EEIVELAESG 180 IRYTQMPHVM EVILPMLCSY MSRWWEHGPE NNPERAEMCC TALNSEHMNT LLGNILKIIY 240 NNLGIDEGAW MKRLAVFSQP IINKVKPQLL KTHFLPLMEK LKKKAATVVS EEDHLKAEAR 300 GDMSEAELLI LDEFTTLARD LYAFYPLLIR FVDYNRAKWL KEPNPEAEEL FRMVAEVFIY 360 WSKSHNFKRE EQNFVVQNEI NNMSFLITDT KSKMSKAAVS DQERKKMKRK GDRYSMQTSL 420 IVAALKRLLP IGLNICAPGD QELIALAKNR FSLKDTEDEV RDIIRSNIHL QGKLEDPAIR 480 WQMALYKDLP NRTDDTSDPE KTVERVLDIA NVLFHLEQKS KRVGRRHYCL VEHPQRSKKA 540 VWHKLLSKQR KRAVVACFRM APLYNLPRHR AVNLFLQGYE KSWIETEEHY FEDKLIEDLA 600 KPGAEPPEED EGTKRVDPLH QLILLFSRTA LTEKCKLEED FLYMAYADIM AKSCHDEEDD 660 DGEEEVKSFE HDIIKDLRNK FASLGENSLE KEMEKQKLLY QQARLHDRGA AEMVLQTISA 720 SKGETGPMVA ATLKLGIAIL NGGNSTVQQK MLDYLKEKKD VGFFQSLAGL MQSCSVLDLN 780 AFERQNKAEG LGMVTEEGSG EKVLQDDEFT CDLFRFLQLL CEGHNSDFQN YLRTQTGNNT 840 TVNIIISTVD YLLRVQESIS DFYWYYSGKD VIDEQGQRNF SKAIQVAKQV FNTLTEYIQG 900 PCTGNQQSLA HSRLWDAVVG FLHVFAHMQM KLSQDSSQIE LLKELMDLQK DMVVMLLSML 960 EGNVVNGTIG KQMVDMLVES SNNVEMILKF FDMFLKLKDL TSSDTFKEYD PDGKGVISKR 1020 DFHKAMESHK HYTQSETEFL LSCAETDENE TLDYEEFVKR FHEPAKDIGF NVAVLLTNLS 1080 EHMPNDTRLQ TFLELAESVL NYFQPFLGRI EIMGSAKRIE RVYFEISESS RTQWEKPQVK 1140 ESKRQFIFDV VNEGGEKEKM ELFVNFCEDT IFEMQLAAQI SESDLNERSA NKEESEKERP 1200 EEQGPRMAFF SILTVRSALF ALRYNILTLM RMLSLKSLKK QMKKVKKMTV KDMVTAFFSS 1260 YWSIFMTLLH FVASVFRGFF RIICSLLLGG SLVEGAKKIK VAELLANMPD PTQDEVRGDG 1320 EEGERKPLEA ALPSEDLTDL KELTEESDLL SDIFGLDLKR EGGQYKLIPH NPNAGLSDLM 1380 SNPVPMPEVQ EKFQEQKAKE EEKEEKEETK SEPEKAEGED G 1421 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:InterPro. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro. GO:0006874; P:cellular calcium ion homeostasis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |