| Tag | Content |
|---|
| CPLM ID | CPLM-003464 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA replication protein DnaC |
Protein Synonyms/Alias | |
Gene Name | dnaC |
Gene Synonyms/Alias | dnaD; b4361; JW4325 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 20 | KMMPAHIKPAFKTGE | acetylation | [1] | | 181 | QTESKYEKVIINQIV | acetylation | [1] | | 211 | SNMEEMTKLLGERVM | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | This protein is required for chromosomal replication. It forms, in concert with DnaB protein and other prepriming proteins DnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'. |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; DNA replication; Nucleotide-binding; Primosome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 245 AA |
Protein Sequence | MKNVGDLMQR LQKMMPAHIK PAFKTGEELL AWQKEQGAIR SAALERENRA MKMQRTFNRS 60
GIRPLHQNCS FENYRVECEG QMNALSKARQ YVEEFDGNIA SFIFSGKPGT GKNHLAAAIC 120
NELLLRGKSV LIITVADIMS AMKDTFRNSG TSEEQLLNDL SNVDLLVIDE IGVQTESKYE 180
KVIINQIVDR RSSSKRPTGM LTNSNMEEMT KLLGERVMDR MRLGNSLWVI FNWDSYRSRV 240
TGKEY 245 |
Gene Ontology | GO:1990077; C:primosome complex; IEA:UniProtKB-KW. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW. GO:0006271; P:DNA strand elongation involved in DNA replication; IGI:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |