CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017628
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myb/SANT-like DNA-binding domain-containing protein 4 
Protein Synonyms/Alias
 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 
Gene Name
 MSANTD4 
Gene Synonyms/Alias
 KIAA1826; DC25 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
9KQLKRKRKSNFSVQEubiquitination[1]
22QETQTLLKEITKRKEubiquitination[1]
209HLLVNIEKQKLELEKubiquitination[2]
273LQIVNSEKPSLENELubiquitination[1, 2, 3]
285NELGQGEKSMLQPQDubiquitination[1, 2, 3]
297PQDIETEKLKLERERmethylation[4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510] 
Functional Description
  
Sequence Annotation
 DOMAIN 4 77 Myb-like.
 MOD_RES 188 188 Phosphothreonine.  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 345 AA 
Protein Sequence
MKQLKRKRKS NFSVQETQTL LKEITKRKEV IFSKQLNTTI NVMKRMAWEE IAQCVNAVGE 60
GEQRTGTEVK RRYLDWRALM KRKRMKANIK LVGSGFPLPS SDLDDSLTEE IDEKIGFRND 120
ANFDWQNVAD FRDAGGSLTE VKVEEEERDP QSPEFEIEEE EEMLSSVIPD SRRENELPDF 180
PHIDEFFTLN STPSRSAYDE PHLLVNIEKQ KLELEKRRLD IEAERLQVEK ERLQIEKERL 240
RHLDMEHERL QLEKERLQIE REKLRLQIVN SEKPSLENEL GQGEKSMLQP QDIETEKLKL 300
ERERLQLEKD RLQFLKFESE KLQIEKERLQ VEKDRLRIQK EGHLQ 345 
Gene Ontology
 GO:0005634; C:nucleus; IDA:LIFEdb. 
Interpro
 IPR026162; MSANTD4. 
Pfam
  
SMART
  
PROSITE
 PS50090; MYB_LIKE 
PRINTS