CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011483
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histone H1t 
Protein Synonyms/Alias
 Testicular H1 histone 
Gene Name
 Hist1h1t 
Gene Synonyms/Alias
 H1ft; H1t 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
28SSKRRGKKPGLAPARacetylation[1]
Reference
 [1] Mass spectrometric mapping of linker histone H1 variants reveals multiple acetylations, methylations, and phosphorylation as well as differences between cell culture and tissue.
 Wisniewski JR, Zougman A, Krüger S, Mann M.
 Mol Cell Proteomics. 2007 Jan;6(1):72-87. [PMID: 17043054
Functional Description
 Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. 
Sequence Annotation
 DOMAIN 38 111 H15.
 MOD_RES 9 9 Phosphoserine.
 MOD_RES 141 141 Phosphoserine.
 MOD_RES 156 156 Phosphothreonine.
 MOD_RES 178 178 Phosphoserine.  
Keyword
 Chromosome; Complete proteome; Developmental protein; Differentiation; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
MSETAPAASS TLVPAPVEKP SSKRRGKKPG LAPARKPRGF SVSKLIPEAL STSQERAGMS 60
LAALKKALAA AGYDVEKNNS RIKLALKRLV NKGVLVQTKG TGASGSFKLS KKAASGNDKG 120
KGKKSASAKA KKMGLPRASR SPKSSKTKAV KKPKATPTKA SGSGRKTKGA KGVQQRKSPA 180
KARAANPNSG KAKMVMQKTD LRKAAGRK 208 
Gene Ontology
 GO:0000794; C:condensed nuclear chromosome; IDA:MGI.
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0007339; P:binding of sperm to zona pellucida; IGI:MGI.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro.
 GO:0030317; P:sperm motility; IGI:MGI.
 GO:0007283; P:spermatogenesis; IGI:MGI. 
Interpro
 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00538; Linker_histone 
SMART
 SM00526; H15 
PROSITE
 PS51504; H15 
PRINTS
 PR00624; HISTONEH5.