CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026142
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell division protein FtsZ 
Protein Synonyms/Alias
  
Gene Name
 ftsZ 
Gene Synonyms/Alias
 TTHA1089 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
56HRIQLGEKLTRGLGAacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity). 
Sequence Annotation
 NP_BIND 96 104 GTP (By similarity).  
Keyword
 Cell cycle; Cell division; Complete proteome; Cytoplasm; GTP-binding; Nucleotide-binding; Reference proteome; Septation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 352 AA 
Protein Sequence
MEGAVIKVIG LGGAGNNAVN RMIEAGLSGV EFIAANTDAQ VLAKSLADHR IQLGEKLTRG 60
LGAGANPEIG EKAALEAEDL IAEALEGADL VFITAGMGGG TGTGSAPVVA DIAKRLGALT 120
VAVVTRPFSF EGPKRMRAAE EGIKKLKERV DAMVVVQNDR LLSAVDKKMT LKDAFLIADR 180
VLYHGVKGIT DVINLPGLIN VDFADVKALL EGAGQVLMGI GAGRGENRVE EAAKSAIHSP 240
LLERSIEGAK RLLLNVVGSE ELSLMEAAEV VERIREATGH EDVDILYGVT YDERAQDELR 300
VILIAAGFAE STVVPRPARP VDFPTGHVDL TNYDIPAFIR YGDGDYPPRR GN 352 
Gene Ontology
 GO:0032153; C:cell division site; IEA:HAMAP.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043234; C:protein complex; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:HAMAP.
 GO:0003924; F:GTPase activity; IEA:HAMAP.
 GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.
 GO:0043093; P:cytokinesis by binary fission; IEA:HAMAP.
 GO:0051258; P:protein polymerization; IEA:HAMAP. 
Interpro
 IPR000158; Cell_div_FtsZ.
 IPR020805; Cell_div_FtsZ_CS.
 IPR024757; FtsZ_C.
 IPR008280; Tub_FtsZ_C.
 IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
 IPR003008; Tubulin_FtsZ_GTPase. 
Pfam
 PF12327; FtsZ_C
 PF00091; Tubulin 
SMART
 SM00864; Tubulin
 SM00865; Tubulin_C 
PROSITE
 PS01134; FTSZ_1
 PS01135; FTSZ_2 
PRINTS
 PR00423; CELLDVISFTSZ.