CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024628
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Muscle-related coiled-coil protein 
Protein Synonyms/Alias
 Muscle-restricted coiled-coil protein 
Gene Name
 Murc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
101RKVSAHIKDVKARVEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway. 
Sequence Annotation
  
Keyword
 Activator; Coiled coil; Complete proteome; Cytoplasm; Developmental protein; Differentiation; Myogenesis; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 362 AA 
Protein Sequence
MEHNGSASNA GKIHQNRLSS VTEDEDQDAA LTIVTVLDRV ATVVDSVQAS QKRIEERHRE 60
MGNAIKSVQI DLLKLSQSHS NTGYVVNKLF EKTRKVSAHI KDVKARVEKQ QVRVTKVETK 120
QEEIMKKNKF RVVIFQEDVP CPASLSVVKD RSLPENEEEA EEVFDPPIDL SSDEEYYVEE 180
SRSARLRKSG KEHIDHIKKA FSKENMQKTR QNFDKKVSGI RTRIVTPERR ERLRQSGERL 240
RQSGERLRQS GERFKKSISN ATPSKEAFKI RSLRKPKDPK AEGQEVDRGM GVDIISGSLA 300
LGPIHEFHSD GFSETEKEVT KVGYIPQEGG DPPTPEPLKV TFKPQVRVED DESLLLELKQ 360
SS 362 
Gene Ontology
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR026752; Cavin_fam. 
Pfam
  
SMART
  
PROSITE
  
PRINTS