| Tag | Content |
|---|
| CPLM ID | CPLM-020646 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 15 |
Protein Synonyms/Alias | GTPase-activating protein RAB7; GAP for RAB7; Rab7-GAP |
Gene Name | Tbc1d15 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 26 | YIHSSCGKANDQDSL | ubiquitination | [1] | | 322 | LVAVESMKQKIFRGG | ubiquitination | [1] | | 352 | YFPWDSTKEERTQLQ | ubiquitination | [1] | | 396 | DYRSLIEKDVNRTDR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6. |
Sequence Annotation | DOMAIN 329 539 Rab-GAP TBC.
MOD_RES 2 2 N-acetylalanine (By similarity).
MOD_RES 70 70 Phosphoserine (By similarity).
MOD_RES 180 180 Phosphotyrosine.
MOD_RES 205 205 Phosphoserine.
MOD_RES 655 655 Phosphoserine (By similarity).
MOD_RES 669 669 Phosphothreonine (By similarity). |
Keyword | Acetylation; Complete proteome; Cytoplasm; GTPase activation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 671 AA |
Protein Sequence | MAAAGVVSGK IIYEQEGVYI HSSCGKANDQ DSLISGILRV LEKDAEVIVD WRPLDDALDS 60
SSILCAGKDS SSVVEWTQAP KERAHRGSDQ QSSYEAEWDM VTTVSFKKKP HTNGDAPGHR 120
NGKSKWSFLF SLADLKSVKQ SKEGMGWSYL VFCLKDDVML PALHFHQGDS KLLIESLEKY 180
VVLCESPQDS RTLLVNCQNK SLSQSFENLL DEPAYGLIQK IKKDPYTATM VGFSKVTNYI 240
FDSLRGSDPS THQRPPSEMA DFLSDAIPGL KINQQEEPGF EVITRIDLGE RPVVQRREPV 300
SLEEWNKSLD PEGRLVAVES MKQKIFRGGL SHSLRKQAWK FLLGYFPWDS TKEERTQLQK 360
QKTDEYFRMK LQWKSVSEAQ EKRNSRLRDY RSLIEKDVNR TDRTNKFYEG QDNPGLILLH 420
DILMTYCMYD FDLGYVQGMS DLLSPLLYVM ENEVDAFWCF ASYMDQMHQN FEEQMQGMKT 480
QLIQLSTLLR LLDSGFCSYL ESQDSGYLYF CFRWLLIRFK REFSFLDILR LWEVMWTELP 540
CKNFHLLLCC AILESEKQQI MAKHYGFNEI LKHINELSMK IDVEDILCKA EAISLQMAQC 600
KELPQAVCEI LGLQDSEITT PDSDTDENVG SPCPVSAFPS STLPILAASE AKDDSPTQTL 660
ASPNACRLTP A 671 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |