UniProt Accession

 SODM_ECOLI; P00448; Q2M8K5 

Genbank Protein ID

 X03951; M20984; L19201; U00096; AP009048; X60699; M85158 

Genbank Nucleotide ID

 CAA27580.1; AAB03041.1; AAC76890.1; BAE77401.1; CAA43108.1; AAA24528.1 

Protein Name

 Superoxide dismutase [Mn] 

Protein Synonyms/Alias

 MnSOD 

Gene Name

 sodA 

Gene Synonyms/Alias

 b3908; JW3879 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
30	TMEIHHTKHHQTYVN	acetylation	[1]
60	PVEELITKLDQLPAD	acetylation	[1]
68	LDQLPADKKTVLRNN	acetylation	[1]
69	DQLPADKKTVLRNNA	acetylation	[1]
87	ANHSLFWKGLKKGTT	acetylation	[1]
90	SLFWKGLKKGTTLQG	acetylation	[1]
91	LFWKGLKKGTTLQGD	acetylation	[1]
100	TTLQGDLKAAIERDF	acetylation	[1]
114	FGSVDNFKAEFEKAA	acetylation	[1, 2]
119	NFKAEFEKAAASRFG	acetylation	[1, 2]
135	GWAWLVLKGDKLAVV	acetylation	[1]
187	NRRPDYIKEFWNVVN	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508] 

Functional Description

 Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. 

Sequence Annotation

 METAL 27 27 Manganese.
 METAL 82 82 Manganese.
 METAL 168 168 Manganese.
 METAL 172 172 Manganese.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Manganese; Metal-binding; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 206 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0003677; F:DNA binding; IDA:EcoCyc.
 GO:0030145; F:manganese ion binding; IDA:EcoCyc.
 GO:0004784; F:superoxide dismutase activity; IDA:EcoCyc.
 GO:0071291; P:cellular response to selenium ion; IEP:EcoCyc.
 GO:0019430; P:removal of superoxide radicals; IDA:EcoliWiki.
 GO:0010447; P:response to acidity; IMP:EcoCyc.
 GO:0009408; P:response to heat; IMP:EcoCyc. 

Interpro

 IPR001189; Mn/Fe_SOD.
 IPR019833; Mn/Fe_SOD_BS.
 IPR019832; Mn/Fe_SOD_C.
 IPR019831; Mn/Fe_SOD_N. 

Pfam

 PF02777; Sod_Fe_C
 PF00081; Sod_Fe_N 

SMART

  

PROSITE

 PS00088; SOD_MN 

PRINTS

 PR01703; MNSODISMTASE.