CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013550
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FAS-associated factor 2 
Protein Synonyms/Alias
 UBX domain-containing protein 8 
Gene Name
 Faf2 
Gene Synonyms/Alias
 Ubxd8 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
68SQALSDAKRELRFLLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome (By similarity). 
Sequence Annotation
 DOMAIN 258 340 UBX.
 MOD_RES 68 68 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Endoplasmic reticulum; Lipid droplet; Reference proteome; Unfolded protein response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 346 AA 
Protein Sequence
MLPFRFTYYT ILDIFRFALR FIRPDPRSRV TDPVGDIVSF MHSFEEKYGR AHPVFYQGTY 60
SQALSDAKRE LRFLLVYLHG DDHQDSDEFC RNALCAPEVI SLINSRMLFW ACSTNKPEGY 120
RVSQALRENT YPFLAMIMLK DRRMTVVGRL EGLIQPDDLI NQLTFIMDAN QTYLVSERLE 180
REERNQTQVL RQQQDEAYLA SLRADQEKER KKREERERKR RKEEEVQQQK LAEERRRQNL 240
QEEKERKLEC LPPEPSPDDP DSVKIIFKLP NDSRVERRFH FSQSLTVIHD FLFSLKESPE 300
KFQIEANFPR RVLPCVPSEE WPNPPTLQEA GLSHTEVLFV QDLTDE 346 
Gene Ontology
 GO:0034098; C:Cdc48p-Npl4p-Ufd1p AAA ATPase complex; IEA:Compara.
 GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.
 GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW. 
Interpro
 IPR006577; UAS.
 IPR001012; UBX. 
Pfam
 PF00789; UBX 
SMART
 SM00594; UAS 
PROSITE
 PS50033; UBX 
PRINTS